Overview

  • Product nameAnti-TLR11 antibody
    See all TLR11 primary antibodies
  • Description
    Rabbit polyclonal to TLR11
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide corresponding to 15 amino acids near the carboxy-terminus of mouse TLR11.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab21274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 2 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 90 kDa.Can be blocked with Active mouse TLR11 peptide (ab39867).
IHC-P Use at an assay dependent concentration.

Target

  • RelevanceToll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
  • Cellular localizationType I membrane protein
  • Database links
  • Alternative names
    • hgnc31753 antibody
    • Toll like receptor 11 antibody

Anti-TLR11 antibody images

  • Western blot analysis of TLR11 in RAW264.7 cell lysates with anti-TLR11 at (A) 0.5 and (B) 1 µg/ml.
  • ab21274 at 2µg/ml staining TLR11 in RAW264.7 cells by ICC/IF

References for Anti-TLR11 antibody (ab21274)

ab21274 has not yet been referenced specifically in any publications.

Product Wall

I can not give out the exact sequences as they are proprietary, but I will give you as much information as possible. Both antigens were selected from accession number NP_991388. Both peptides are within the last 100 residues of TLR11 with ab21274 clos...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"