Overview

  • Product nameAnti-TLR11 antibody
    See all TLR11 primary antibodies
  • Description
    Rabbit polyclonal to TLR11
  • Specificityab24183 reacts with toll-like receptor 11(TLR11)
  • Tested applicationsSuitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide (Mouse) corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11(GenBank accession no. NP_991388).

  • Positive control
    • RAW264.7 cell lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab24183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 105 kDa).Can be blocked with Active mouse TLR11 peptide (ab39868).

Target

  • RelevanceToll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
  • Cellular localizationType I membrane protein
  • Database links
  • Alternative names
    • hgnc31753 antibody
    • Toll like receptor 11 antibody

Anti-TLR11 antibody images

  • Lane 1 : Anti-TLR11 antibody (ab24183) at 0.5 µg/ml
    Lane 2 : Anti-TLR11 antibody (ab24183) at 1 µg/ml
    Lane 3 : Anti-TLR11 antibody (ab24183) at 2 µg/ml

    Lane 1 : RAW 264.7 cell lysate.
    Lane 2 : RAW 264.7 cell lysate.
    Lane 3 : RAW 264.7 cell lysate.


    Predicted band size : 105 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
  • ab24183 at 10µg/ml staining of TLR11 in RAW264.7 cells by ICC/IF

References for Anti-TLR11 antibody (ab24183)

ab24183 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"