Overview

  • Product nameAnti-TLR6 antibody
    See all TLR6 primary antibodies
  • Description
    Rabbit polyclonal to TLR6
  • Specificityab62569 does not recognize TLR1.
  • Tested applicationsSuitable for: ICC, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A peptide corresponding to 13 amino acids near the centre of human TLR6.

  • Positive control
    • Jurkat cell lysate. Jurkat cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab62569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use a concentration of 2 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 92 kDa).

Target

  • FunctionParticipates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.
  • Tissue specificityDetected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
  • Sequence similaritiesBelongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • Cellular localizationCell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD286 antibody
    • CD286 antigen antibody
    • TLR 6 antibody
    • Tlr6 antibody
    • TLR6_HUMAN antibody
    • Toll like receptor 6 precursor antibody
    • Toll-like receptor 6 antibody
    see all

Anti-TLR6 antibody images

  • Lane 1 : Anti-TLR6 antibody (ab62569) at 0.5 µg/ml
    Lane 2 : Anti-TLR6 antibody (ab62569) at 1 µg/ml
    Lane 3 : Anti-TLR6 antibody (ab62569) at 2 µg/ml

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate
    Lane 3 : Jurkat cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 92 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 110 kDa. We are unsure as to the identity of these extra bands.
  • ab62569, at 2µg/ml, staining TLR6 in Jurkat cells by immunocytochemistry.

References for Anti-TLR6 antibody (ab62569)

ab62569 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab62569.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"