Anti-TMC6 antibody (ab67325)

Overview

  • Product nameAnti-TMC6 antibody
    See all TMC6 primary antibodies
  • Description
    Rabbit polyclonal to TMC6
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    a 14 amino acid synthetic peptide from near the amino terminus of human TMC6.

  • Positive control
    • A20 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab67325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa).
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • RelevanceDefects in TMC6 are a cause of epidermodysplasia verruciformis, a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions. TMC6 is expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes. There are four named isoforms.
  • Cellular localizationEndoplasmic reticulum membrane; Multi-pass membrane protein
  • Database links
  • Alternative names
    • Epidermodysplasia verruciformis protein 1 antibody
    • EV1 antibody
    • EVER1 antibody
    • EVIN1 antibody
    • LAK 4P antibody
    • LAK4P antibody
    • Protein LAK 4 antibody
    • Protein LAK4 antibody
    • Transmembrane channel like protein 6 antibody
    see all

Anti-TMC6 antibody images

  • Lane 1 : Anti-TMC6 antibody (ab67325) at 1 µg/ml
    Lane 2 : Anti-TMC6 antibody (ab67325) at 2 µg/ml

    Lane 1 : A20 cell lysate
    Lane 2 : A20 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 90 kDa
    Observed band size : 90 kDa
  • ab67325 at 2.5 µg/ml staining TMC6 in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

References for Anti-TMC6 antibody (ab67325)

ab67325 has not yet been referenced specifically in any publications.

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Chinese Hamster Cell (CHO)
Specification CHO
Fixative Formaldehyde
Permeabilization Yes - triton
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10µg/mL · Temperature: 25°C
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Verified customer

Submitted Apr 15 2013

Thank you for your inquiry.

Unfortunately, we are not able to release the immunogen sequence for ab67325 and ab69859 as it is proprietary information.

However, I can tell you that ab67325 is against a peptide from within xxxxx of ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"