Overview

  • Product name
  • Description
    Rabbit polyclonal to TMED3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 120-173 of Human TMED3, isoform 2 (UniProt ID: Q9Y3Q3-2).

  • Positive control
    • Human placenta tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab151056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
  • Sequence similarities
    Belongs to the EMP24/GP25L family.
    Contains 1 GOLD domain.
  • Cellular localization
    Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus > cis-Golgi network membrane. Golgi apparatus > Golgi stack membrane. Endoplasmic reticulum membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. Probably cycles between compartments of the early secretatory pathway.
  • Information by UniProt
  • Database links
  • Alternative names
    • C15orf22 antibody
    • Integral type I protein antibody
    • Membrane protein p24B antibody
    • p24 family protein gamma 4 antibody
    • p24 family protein gamma-4 antibody
    • P24B antibody
    • p24g4 antibody
    • p24gamma4 antibody
    • p26 antibody
    • Testis tissue sperm binding protein Li 48e antibody
    • Tmed3 antibody
    • TMED3_HUMAN antibody
    • Transmembrane emp24 domain containing protein 3 antibody
    • Transmembrane emp24 domain-containing protein 3 antibody
    • Transmembrane p24 trafficking protein 3 antibody
    • UNQ5357/PRO1078 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human placenta tissue labeling TMED3 with ab151056 at a 1/10 dilution.

References

This product has been referenced in:
  • Zheng H  et al. TMED3 promotes hepatocellular carcinoma progression via IL-11/STAT3 signaling. Sci Rep 6:37070 (2016). WB ; Human . Read more (PubMed: 27901021) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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