Anti-TMEM119 antibody - Microglial marker (ab185337)
Key features and details
- Rabbit polyclonal to TMEM119 - Microglial marker
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TMEM119 antibody - Microglial marker
See all TMEM119 primary antibodies -
Description
Rabbit polyclonal to TMEM119 - Microglial marker -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human TMEM119 aa 100-200.
Database link: Q4V9L6 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab185337 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | (2) |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Cellular localization
Membrane; Single-pass type I membrane protein -
Database links
- Entrez Gene: 338773 Human
- SwissProt: Q4V9L6 Human
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Alternative names
- OBIF antibody
- Osteoblast induction factor antibody
- PSEC0199 antibody
see all
Images
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Paraffin-embedded human lymph node tissue stained for TMEM119 using ab185337 at 1/50 dilution in immunohistochemical analysis.
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Paraffin-embedded human cerebral cortex tissue stained for TMEM119 using ab185337 at 1/50 dilution in immunohistochemical analysis.
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Paraffin-embedded human testis tissue stained for TMEM119 using ab185337 at 1/50 dilution in immunohistochemical analysis.
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Paraffin-embedded human liver tissue stained for TMEM119 using ab185337 at 1/50 dilution in immunohistochemical analysis.
Negative control.
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Immunohistochemistry analysis of Human tonsil tissue labeling TMEM119 with ab185337 at 1/50 dilution.
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab185337 has been referenced in 5 publications.
- Hase Y et al. Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke. Brain Pathol 32:e13101 (2022). PubMed: 35748290
- Vahsen BF et al. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons. Sci Rep 12:12606 (2022). PubMed: 35871163
- Liu W et al. Human Inner Ear Immune Activity: A Super-Resolution Immunohistochemistry Study. Front Neurol 10:728 (2019). PubMed: 31354608
- Sellgren CM et al. Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors. Mol Psychiatry 22:170-177 (2017). ICC/IF ; Human . PubMed: 27956744
- Sanchez JJ et al. Prenatal alcohol exposure is a risk factor for adult neuropathic pain via aberrant neuroimmune function. J Neuroinflammation 14:254 (2017). IHC-P ; Rat . PubMed: 29258553