• Product nameAnti-TMEM43 antibody
    See all TMEM43 primary antibodies
  • Description
    Rabbit polyclonal to TMEM43
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 194-223 of Human TMEM43 (NP_077310.1).

  • Positive control
    • MDA-MB231 cell line lysate.



Our Abpromise guarantee covers the use of ab113116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 45 kDa.


  • FunctionMay have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane.
  • Tissue specificityHighest expression in placenta. Also found at lower levels in heart, ovary, spleen, small intestine, thymus, prostate and testis.
  • Involvement in diseaseDefects in TMEM43 are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5) [MIM:604400]; also known as arrhythmogenic right ventricular cardiomyopathy (ARVC5). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • Sequence similaritiesBelongs to the TMEM43 family.
  • Cellular localizationEndoplasmic reticulum. Nucleus inner membrane. Retained in the inner nuclear membrane through interaction with EMD and A-and B-lamins. The N- and C-termini are orientated towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARVC5 antibody
    • ARVD5 antibody
    • EDMD7 antibody
    • LUMA antibody
    • Protein LUMA antibody
    • Tmem43 antibody
    • TMM43_HUMAN antibody
    • Transmembrane protein 43 antibody
    see all

Anti-TMEM43 antibody images

  • Anti-TMEM43 antibody (ab113116) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 45 kDa

References for Anti-TMEM43 antibody (ab113116)

ab113116 has not yet been referenced specifically in any publications.

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