Overview

  • Product name
  • Description
    Rabbit polyclonal to TMEM49
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 376-406 of Human TMEM49 (NP_112200.2).

  • Positive control
    • HepG2 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 46 kDa.

Target

  • Function
    Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
  • Sequence similarities
    Belongs to the VMP1 family.
  • Cellular localization
    Endoplasmic reticulum-Golgi intermediate compartment membrane. Cell membrane. Vacuole membrane. Endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZP566I133 antibody
    • ectopic P-granules autophagy protein 3 homolog antibody
    • NF E2 induceble protein 2 antibody
    • NF E2 inducible protein 2 antibody
    • ni 2 antibody
    • protein ni 2 antibody
    • Tango5 antibody
    • TDC1 antibody
    • TMEM49 antibody
    • Transmembrane protein 49 antibody
    • transport and golgi organization 5 homolog antibody
    • Vacuole membrane protein 1 antibody
    • vmp1 antibody
    • VMP1_HUMAN antibody
    see all

Images

  • Anti-TMEM49 antibody (ab116006) at 1/100 dilution + HepG2 cell line lysate at 35 µg

    Predicted band size : 46 kDa

References

ab116006 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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