Overview

  • Product name
  • Description
    Rabbit polyclonal to TMEM59L
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 148-261 of Human TMEM59L.

  • Positive control
    • Human cerebral cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab121321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding.
  • Tissue specificity
    Expressed preferentially at high level in the brain.
  • Sequence similarities
    Belongs to the TMEM59 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • BSMAP antibody
    • Brain-specific membrane-anchored protein antibody
    • C19orf4 antibody
    • TM59L_HUMAN antibody
    • Tmem59l antibody
    • Transmembrane protein 59-like antibody
    • Transmembrane protein 59L antibody
    see all

Images

  • ab121321 at 1/25 dilution staining TMEM59L in Paraffin-embedded Human cerebral cortex tissue by Immunohistochemistry.

References

ab121321 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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