Overview

  • Product name
  • Description
    Rabbit polyclonal to TMEM70
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide of Human TMEM70, conjugated to KLH.

  • Positive control
    • Human small intestine tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab113705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 29 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    Involved in biogenesis of mitochondrial ATP synthase.
  • Involvement in disease
    Defects in TMEM70 are a cause of mitochondrial encephalocardiomyopathy neonatal due to ATP synthase deficiency (MT-ATPSD) [MIM:604273]; also known as ATPase deficiency. A mitochondrial disorder with heterogeneous clinical manifestations including dysmorphic features, psychomotor retardation, hypotonia, growth retardation, cardiomyopathy, enlarged liver, hypoplastic kidneys and elevated lactate levels in urine, plasma and cerebrospinal fluid.
  • Sequence similarities
    Belongs to the TMEM70 family.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ20533 antibody
    • MC5DN2 antibody
    • OTTHUMP00000226855 antibody
    • OTTHUMP00000226856 antibody
    • TMEM70 antibody
    • TMM70_HUMAN antibody
    • Transmembrane protein 70 antibody
    • Transmembrane protein 70 mitochondrial antibody
    • Transmembrane protein 70, mitochondrial antibody
    see all

Images

  • ab113705, at 5 µg/ml, staining TMEM70 in formalin fixed, paraffin embedded Human small intestine tissue by Immunohistochemistry.

References

ab113705 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab113705.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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