Overview

  • Product name
  • Description
    Goat polyclonal to TMPRSS4
  • Specificity
    ab82176 is expected to recognize both reported isoforms (NP_063947.1 and NP_001077416.1).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    DSTRCNADDAYQGE

    , corresponding to internal sequence amino acids 352-365 of Human TMPRSS4 (NP_063947.1) (or aa347-360 of NP_001077416.1).

  • Positive control
    • Human Bone Marrow lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab82176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 48 kDa.

Target

  • Function
    Probable protease. Seems to be capable of activating ENaC.
  • Tissue specificity
    High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.
  • Sequence similarities
    Belongs to the peptidase S1 family.
    Contains 1 LDL-receptor class A domain.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • UNQ776/PRO1570 antibody
    • CAPH2 antibody
    • Channel-activating protease 2 antibody
    • Membrane type serine protease 2 antibody
    • Membrane-type serine protease 2 antibody
    • MT SP2 antibody
    • MT-SP2 antibody
    • TMPRSS 4 antibody
    • TMPRSS3 antibody
    • TMPRSS4 antibody
    • TMPS4_HUMAN antibody
    • Transmembrane protease serine 4 antibody
    • Transmembrane protease, serine 4 antibody
    • Transmembrane serine protease 3 antibody
    see all

Images

  • Anti-TMPRSS4 antibody (ab82176) at 1 µg/ml + Human Bone Marrow lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 48 kDa
    Observed band size : 48 kDa

References

This product has been referenced in:
  • Li XM  et al. Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer. Int J Mol Med 39:927-935 (2017). Read more (PubMed: 28259959) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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