Overview

  • Product name
  • Description
    Rabbit polyclonal to TMPRSS5
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 175-402 of Human TMPRSS5 (AAI21804).

  • Positive control
    • MCF7 cells and whole cell lysate; U373 xenograft tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 20% Glycerol, 0.75% Glycine
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 46 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

Target

  • Function
    May play a role in hearing.
  • Tissue specificity
    Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.
  • Involvement in disease
    Note=Defects in TMPRSS5 may be a cause of deafness.
  • Sequence similarities
    Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC141886 antibody
    • MGC148044 antibody
    • OTTHUMP00000238209 antibody
    • OTTHUMP00000238210 antibody
    • OTTHUMP00000238211 antibody
    • OTTHUMP00000238212 antibody
    • OTTHUMP00000238213 antibody
    • Spinesin antibody
    • TMPRSS 5 antibody
    • TMPRSS5 antibody
    • TMPS5_HUMAN antibody
    • Transmembrane protease serine 5 antibody
    • Transmembrane protease, serine 5 (spinesin) antibody
    • Transmembrane protease, serine 5 antibody
    see all

Images

  • Anti-TMPRSS5 antibody (ab111695) at 1/1000 dilution + MCF7 whole cell lysate at 30 µg

    Predicted band size : 46 kDa
  • ab111695 at 1/200 dilution staining TMPRSS5 in methanol-fixed MCF7 cells by Immunofluorescence. Lower image shows cells co-stained with Hoechst 33342.
  • ab111695 at 1/500 dilution staining TMPRSS5 in Formalin-fixed, paraffin-embedded U373 xenograft tissue by Immunohistochemistry.

References

ab111695 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab111695.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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