Overview

  • Product nameAnti-TMPRSS5 antibody
    See all TMPRSS5 primary antibodies
  • Description
    Goat polyclonal to TMPRSS5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide:

    LDWIHDTAQDSLL

    , corresponding to C terminal amino acids 445-457 of Human TMPRSS5

  • General notesPrincipal Names - TMPRSS5; transmembrane protease, serine 5 (spinesin); SPINESIN; spinesin. Official Gene Symbol - TMPRSS5. GenBank Accession Number – NP_110397. LocusLink ID - 80975

Properties

Applications

Our Abpromise guarantee covers the use of ab2245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1 - 3 µg/ml. Detects two bands of approximately 35 and 52 kDa in mouse brain lysate.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play a role in hearing.
    • Tissue specificityBrain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.
    • Involvement in diseaseNote=Defects in TMPRSS5 may be a cause of deafness.
    • Sequence similaritiesBelongs to the peptidase S1 family.
      Contains 1 peptidase S1 domain.
      Contains 1 SRCR domain.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • MGC141886 antibody
      • MGC148044 antibody
      • OTTHUMP00000238209 antibody
      • OTTHUMP00000238210 antibody
      • OTTHUMP00000238211 antibody
      • OTTHUMP00000238212 antibody
      • OTTHUMP00000238213 antibody
      • Spinesin antibody
      • TMPRSS 5 antibody
      • TMPRSS5 antibody
      • TMPS5_HUMAN antibody
      • Transmembrane protease serine 5 antibody
      • Transmembrane protease, serine 5 (spinesin) antibody
      • Transmembrane protease, serine 5 antibody
      see all

    Anti-TMPRSS5 antibody images

    • ab2245 staining (2µg/ml) of Mouse Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
    • ab2245 staining (0.5µg/ml) of Human Brain (Cerebral Cortex) lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

    References for Anti-TMPRSS5 antibody (ab2245)

    ab2245 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry and your patience, the source of ab2245 has confirmed that Western blots were done using reducing conditions. The exact protocol is below: - SDS PAGE. Samples were run at 200V constant on a 12% acrylamide SDS-PAGE min...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"