Overview

  • Product name
  • Description
    Goat polyclonal to TMPRSS5
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide:

    LDWIHDTAQDSLL

    , corresponding to C terminal amino acids 445-457 of Human TMPRSS5

  • General notes
    Principal Names - TMPRSS5; transmembrane protease, serine 5 (spinesin); SPINESIN; spinesin. Official Gene Symbol - TMPRSS5. GenBank Accession Number – NP_110397. LocusLink ID - 80975

Properties

Applications

Our Abpromise guarantee covers the use of ab2245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1 - 3 µg/ml. Detects two bands of approximately 35 and 52 kDa in mouse brain lysate.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May play a role in hearing.
    • Tissue specificity
      Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.
    • Involvement in disease
      Note=Defects in TMPRSS5 may be a cause of deafness.
    • Sequence similarities
      Belongs to the peptidase S1 family.
      Contains 1 peptidase S1 domain.
      Contains 1 SRCR domain.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • MGC141886 antibody
      • MGC148044 antibody
      • OTTHUMP00000238209 antibody
      • OTTHUMP00000238210 antibody
      • OTTHUMP00000238211 antibody
      • OTTHUMP00000238212 antibody
      • OTTHUMP00000238213 antibody
      • Spinesin antibody
      • TMPRSS 5 antibody
      • TMPRSS5 antibody
      • TMPS5_HUMAN antibody
      • Transmembrane protease serine 5 antibody
      • Transmembrane protease, serine 5 (spinesin) antibody
      • Transmembrane protease, serine 5 antibody
      see all

    Images

    • ab2245 staining (2µg/ml) of Mouse Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
    • ab2245 staining (0.5µg/ml) of Human Brain (Cerebral Cortex) lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

    References

    This product has been referenced in:

    See 1 Publication for this product

    Customer reviews and Q&As

    Thank you for your enquiry and your patience, the source of ab2245 has confirmed that Western blots were done using reducing conditions. The exact protocol is below: - SDS PAGE. Samples were run at 200V constant on a 12% acrylamide SDS-PAGE min...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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