• Product nameAnti-TNF beta antibody
    See all TNF beta primary antibodies
  • Description
    Rabbit polyclonal to TNF beta
  • Specificityab106353 does not react with other proteins
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Mouse, Rat, Dog, Human
  • Immunogen

    Synthetic peptide:


    , corresponding to internal sequence amino acids 73-88 of Human TNF beta

  • Positive control
    • Recombinant Human TNF beta protein



Our Abpromise guarantee covers the use of ab106353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa.


  • FunctionCytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
  • Involvement in diseaseGenetic variations in LTA are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).
  • Sequence similaritiesBelongs to the tumor necrosis factor family.
  • Cellular localizationSecreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
  • Information by UniProt
  • Database links
  • Alternative names
    • LTalpha antibody
    • DIF antibody
    • LT alpha antibody
    • LT antibody
    • LT-alpha antibody
    • Lta antibody
    • Lymphotoxin alpha (TNF superfamily, member 1) antibody
    • Lymphotoxin alpha antibody
    • Lymphotoxin-alpha antibody
    • TNF B antibody
    • TNF superfamily member 1 antibody
    • TNF, lymphocyte-derived antibody
    • TNF-beta antibody
    • TNFB antibody
    • TNFB_HUMAN antibody
    • TNFbeta antibody
    • TNFSF1 antibody
    • TNLG1E antibody
    • Tumor necrosis factor beta antibody
    • tumor necrosis factor ligand 1E antibody
    • Tumor necrosis factor ligand superfamily member 1 antibody
    see all

Anti-TNF beta antibody images

  • All lanes : Anti-TNF beta antibody (ab106353) at 1 µg/ml

    Lane 1 : Recombinant Human TNF beta protein at 20ng
    Lane 2 : Recombinant Human TNF beta protein at 5ng
    Lane 3 : Recombinant Human TNF beta protein at 2.5ng

    Predicted band size : 22 kDa

References for Anti-TNF beta antibody (ab106353)

ab106353 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106353.
Please use the links above to contact us or submit feedback about this product.