Overview

  • Product nameAnti-TNF beta antibody (Biotin)
    See all TNF beta primary antibodies
  • Description
    Rabbit polyclonal to TNF beta (Biotin)
  • ConjugationBiotin
  • Tested applicationsELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human).

Properties

Applications

Our Abpromise guarantee covers the use of ab12787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: Use at a concentration of 0.15 - 0.3 µg/ml. Sensitivity = 0.2 ng/well
    WB: Use at a concentration of 0.10 - 0.20 µg/ml. Predicted molecular weight: 24.6 kDa. Sensitivity = 1.5-3.0 ng/lane

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
    • Involvement in diseaseGenetic variations in LTA are a cause of susceptibility psoriatic arthritis (PSORAS) [MIM:607507]. PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).
    • Sequence similaritiesBelongs to the tumor necrosis factor family.
    • Cellular localizationSecreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.
    • Information by UniProt
    • Database links
    • Alternative names
      • LTalpha antibody
      • Coley’s toxin antibody
      • DIF antibody
      • Differentiation inducing factor antibody
      • Hemorrhagic factor antibody
      • LT alpha antibody
      • LT antibody
      • LT-alpha antibody
      • LTA antibody
      • LTA antibody
      • LTalpha antibody
      • Lymphotoxin alpha (TNF superfamily, member 1) antibody
      • Lymphotoxin alpha antibody
      • Lymphotoxin-alpha antibody
      • Natural killer cytotoxic factor antibody
      • Necrosin antibody
      • NKCF antibody
      • OTTHUMP00000037612 antibody
      • OTTHUMP00000037613 antibody
      • TNF B antibody
      • TNF superfamily member 1 antibody
      • TNF-beta antibody
      • TNFB antibody
      • TNFB_HUMAN antibody
      • TNFbeta antibody
      • TNFSF 1 antibody
      • TNFSF1 antibody
      • Tumor necrosis factor beta antibody
      • Tumor necrosis factor ligand superfamily member 1 antibody
      • Tumor necrosis factor superfamily member 1 antibody
      see all

    References for Anti-TNF beta antibody (Biotin) (ab12787)

    ab12787 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"