• Product nameAnti-TNFAIP1 antibody
    See all TNFAIP1 primary antibodies
  • Description
    Rabbit polyclonal to TNFAIP1
  • SpecificityThis antibody detects endogenous levels of total TNFAIP1 protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthesized peptide derived from an internal region of human TNFAIP1.

  • Positive control
    • Extracts from HUVEC cells.


  • FormLiquid
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°C
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab72626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesELISA: 1/5000.
    WB: 1/500 - 1/1000. Detects bands of approximately 34, 60 and 68 kDa (predicted molecular weight: 36 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSubstrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
    • PathwayProtein modification; protein ubiquitination.
    • Sequence similaritiesBelongs to the BACURD family.
      Contains 1 BTB (POZ) domain.
    • Post-translational
      Phosphorylation at Ser-280 by CK2 facilitates the nucleus localization and increases interaction with PCNA.
    • Cellular localizationCytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • alpha-induced protein 1 antibody
      • BACD2_HUMAN antibody
      • BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody
      • BTB/POZ domain-containing protein TNFAIP1 antibody
      • endothelial antibody
      • hBACURD2 antibody
      • Protein B12 antibody
      • tnfaip1 antibody
      • Tumor necrosis factor alpha induced protein 1 (endothelial) antibody
      • Tumor necrosis factor alpha induced protein 1 antibody
      • Tumor necrosis factor antibody
      see all

    Anti-TNFAIP1 antibody images

    • All lanes : Anti-TNFAIP1 antibody (ab72626) at 1/500 dilution

      Lane 1 : Extracts from HUVEC cells, plus PMA (125ng/ml, 30mins)
      Lane 2 : Extracts from HUVEC cells, plus serum (20%, 30mins)
      Lane 3 : Extracts from HUVEC cells, plus PMA (125ng/ml, 30mins) and serum (20%, 30mins) plus immunizing peptide

      Lysates/proteins at 5 µg per lane.

      Predicted band size : 36 kDa
      Observed band size : 34 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 60 and 68 kDa. We are unsure as to the identity of these extra bands.

    References for Anti-TNFAIP1 antibody (ab72626)

    ab72626 has not yet been referenced specifically in any publications.

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