Overview

  • Product nameAnti-TNFAIP8 antibody
    See all TNFAIP8 primary antibodies
  • Description
    Rabbit polyclonal to TNFAIP8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 50-78 of Human TNFAIP8 (NP_055165.2, NP_001071122.1).

  • Positive control
    • K562 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab107684 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 23 kDa.

Target

  • FunctionActs as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
  • Tissue specificityExpressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle.
  • Sequence similaritiesBelongs to the TNFAIP8 family.
  • Developmental stageExpressed at high levels in the fetal liver, lung and kidney.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • GG2 1 antibody
    • Head and neck tumor and metastasis-related protein antibody
    • MDC-3.13 antibody
    • NDED antibody
    • NF-kappa-B-inducible DED-containing protein antibody
    • SCC S2 antibody
    • SCC-S2 antibody
    • SCCS2 antibody
    • TFIP8_HUMAN antibody
    • TNF alpha-induced protein 8 antibody
    • TNF induced protein antibody
    • TNF-induced protein GG2-1 antibody
    • TNFAIP 8 antibody
    • TNFAIP8 antibody
    • Tumor necrosis factor alpha induced protein 8 antibody
    • Tumor necrosis factor alpha-induced protein 8 antibody
    see all

Anti-TNFAIP8 antibody images

  • Anti-TNFAIP8 antibody (ab107684) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 23 kDa

References for Anti-TNFAIP8 antibody (ab107684)

ab107684 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"