Overview

  • Product name
  • Description
    Rabbit polyclonal to TNFRSF14
  • Tested applications
    Suitable for: WB, ICC/IF, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A 16 amino acid peptide from near the carboxy terminus of human TNFRSF14.

  • Positive control
    • Raji cell lysate. Raji cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab62462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 31 kDa).
ICC/IF Use a concentration of 20 µg/ml.
ICC Use a concentration of 10 µg/ml.

Target

  • Function
    Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
  • Tissue specificity
    Widely expressed, with the highest expression in lung, spleen and thymus.
  • Sequence similarities
    Contains 3 TNFR-Cys repeats.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HVEML antibody
    • ATAR antibody
    • CD270 antibody
    • CD40 like protein precursor antibody
    • Herpes virus entry mediator A antibody
    • Herpesvirus entry mediator A antibody
    • Herpesvirus entry mediator antibody
    • Herpesvirus entry mediator ligand antibody
    • HveA antibody
    • HVEM antibody
    • HVEM L antibody
    • LIGHT antibody
    • LIGHTR antibody
    • TNFRSF14 antibody
    • TNFSF 14 antibody
    • TNR14_HUMAN antibody
    • TR2 antibody
    • Tumor necrosis factor receptor like gene2 antibody
    • Tumor necrosis factor receptor superfamily member 14 antibody
    • Tumor necrosis factor receptor superfamily member 14 precursor antibody
    • Tumor necrosis factor receptor-like 2 antibody
    see all

Images

  • All lanes : Anti-TNFRSF14 antibody (ab62462) at 2 µg/ml

    Lane 1 : Raji cell lysate with no blocking peptide
    Lane 2 : Raji cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 31 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)
  • Immunocytochemistry of TNFRSF14 in Raji cells with ab62462 antibody at 10 µg/ml.
  • Immunofluorescence of TNFRSF14 in Raji cells using ab62462 at 20 ug/ml.

References

ab62462 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab62462.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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