Anti-TNFRSF18 antibody [RM0066-7C13] (ab86574)

Overview

  • Product name
    Anti-TNFRSF18 antibody [RM0066-7C13]
    See all TNFRSF18 primary antibodies
  • Description
    Rat monoclonal [RM0066-7C13] to TNFRSF18
  • Tested applications
    Suitable for: IHC-P, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Tissue/ cell preparation of Mouse T cells

  • Positive control
    • Spleen, lung and kidney tissue sections from LPS treated mice

Properties

Applications

Our Abpromise guarantee covers the use of ab86574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
Flow Cyt 1/50 - 1/1000.

Target

  • Function
    Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
  • Tissue specificity
    Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
  • Sequence similarities
    Contains 3 TNFR-Cys repeats.
  • Cellular localization
    Secreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activation inducible TNFR family receptor antibody
    • Activation-inducible TNFR family receptor antibody
    • AITR antibody
    • CD357 antibody
    • GITR antibody
    • GITR D antibody
    • GITR-D antibody
    • GITRD antibody
    • Glucocorticoid induced TNFR related protein antibody
    • glucocorticoid-induced tnf receptor ligand antibody
    • glucocorticoid-induced tnf receptors ligand antibody
    • Glucocorticoid-induced TNFR-related protein antibody
    • TNF receptor superfamily activation inducible protein antibody
    • TNFRSF 18 antibody
    • TNFRSF18 antibody
    • TNR18_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 18 antibody
    • Tumor necrosis factor receptor superfamily member 18 precursor antibody
    see all

Images

  • ab86574 at a 1/50 dilution staining TNFRSF18 by immunohistochemistry in 4% PFA fixed/paraffin embedded spleen tissue sections from a mouse treated with LPS.
  • ab86574 at a 1/50 dilution staining TNFRSF18 by immunohistochemistry in a 4% PFA fixed/paraffin embedded lung tissue section from a mouse treated with LPS.
  • ab86574 at a 1/50 dilution staining TNFRSF18 by immunohistochemistry in a 4% PFA fixed/paraffin embedded lidney tissue section from a mouse treated with LPS.

References

ab86574 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

I can now confirm that Anti-TNFRSF18 antibody [RM0066-7C13] (ab86574) has been used in conjunction withproteinase K treatment. This was performed by using proteinase K (20ug/ml) in PBS to treat the sectionsfor 15-30 minutes at room temperature. The len...

Read More

Thank you for contacting us.

I have some further information to share with you in regards to the antibodies ab119904, ab79056 and ab86574.

Anti-CD134 / OX40 (ab119904)

This antibody was used in staining of paraffin embedde...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up