Overview

  • Product name
  • Description
    Rabbit polyclonal to TNFSF18
  • Specificity
    ab25948 recognises GITRL.
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Purified recombinant full length protein (Human)

  • Positive control
    • THP-1 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab25948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 20 kDa).

Target

  • Function
    Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.
  • Tissue specificity
    Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
  • Sequence similarities
    Belongs to the tumor necrosis factor family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activation inducible TNF related ligand antibody
    • Activation-inducible TNF-related ligand antibody
    • AITR ligand antibody
    • AITRL antibody
    • GITR ligand antibody
    • GITRL antibody
    • Glucocorticoid induced TNF related ligand antibody
    • Glucocorticoid induced TNFR related protein ligand antibody
    • Glucocorticoid-induced TNF-related ligand antibody
    • hGITRL antibody
    • MGC138237 antibody
    • TL6 antibody
    • TNF18_HUMAN antibody
    • TNFSF18 antibody
    • TNLG2A antibody
    • Tumor necrosis factor (ligand) superfamily member 18 antibody
    • Tumor necrosis factor ligand 2A antibody
    • Tumor necrosis factor ligand superfamily member 18 antibody
    see all

Images

  • All lanes : Anti-TNFSF18 antibody (ab25948) at 1 µg/ml

    Lane 1 : 5ng of purified recombinant TNFSF18
    Lane 2 : 25ng of purified recombinant TNFSF18
    Lane 3 : 50ng of purified recombinant TNFSF18


    Predicted band size : 20 kDa
  • ab25948 at 10µg/ml staining TNFSF18 in THP-1 cells by ICC/IF

References

ab25948 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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