Overview

  • Product nameAnti-Tnk1 antibody
    See all Tnk1 primary antibodies
  • Description
    Rabbit polyclonal to Tnk1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tnk1 recombinant protein.

  • Positive control
    • T47D cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab102984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 72 kDa.

Target

  • FunctionInvolved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
  • Tissue specificityExpressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family.
    Contains 1 protein kinase domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Autophosphorylated on tyrosine residues.
  • Cellular localizationCytoplasm. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD38 negative kinase 1 antibody
    • EC 2.7.10.2 antibody
    • Kinase of embryonic stem cells antibody
    • Kos 1 antibody
    • Kos1 antibody
    • MGC46193 antibody
    • Non receptor tyrosine protein kinase TNK 1 antibody
    • Non receptor tyrosine protein kinase TNK1 antibody
    • Non-receptor tyrosine-protein kinase TNK1 antibody
    • Tnk 1 antibody
    • Tnk1 antibody
    • TNK1_HUMAN antibody
    • Tyrosine kinase non receptor 1 antibody
    see all

Anti-Tnk1 antibody images

  • Anti-Tnk1 antibody (ab102984) at 1/100 dilution + T47D cell line lysate at 35 µg

    Predicted band size : 72 kDa

References for Anti-Tnk1 antibody (ab102984)

ab102984 has not yet been referenced specifically in any publications.

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