Overview

  • Product name
  • Description
    Rabbit polyclonal to TNRC5
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Horse, Cow, Cat, Dog, Pig
  • Immunogen

    A region within synthetic peptide: GGKKSKKKSS RAKAAGGRSS SSKQRKELGG LEGDPSPEED EGIQKASPLT, corresponding to amino acids 222-271 of Human TNRC5

  • Positive control
    • Jurkat cell lysate and Human muscle tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.25 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 31 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

Target

  • Function
    Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses.
  • Sequence similarities
    Belongs to the canopy family.
    Contains 1 saposin B-type domain.
  • Cellular localization
    Endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAG repeat containing antibody
    • CAG4A antibody
    • Canopy 3 homolog antibody
    • cnpy3 antibody
    • CNPY3_HUMAN antibody
    • CTG repeat protein 4a antibody
    • ERDA 5 antibody
    • ERDA5 antibody
    • Expanded repeat domain CAG/CTG 5 antibody
    • Expanded repeat-domain protein CAG/CTG 5 antibody
    • OTTHUMP00000016408 antibody
    • PRAT4A antibody
    • Protein associated with Tlr4 antibody
    • Protein associated with Toll like receptor 4A antibody
    • Protein canopy homolog 3 antibody
    • TNRC 5 antibody
    • Trinucleotide repeat containing 5 antibody
    • Trinucleotide repeat-containing gene 5 protein antibody
    see all

Anti-TNRC5 antibody images

  • Anti-TNRC5 antibody (ab56238) at 0.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 31 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human muscle tissue labelling TNRC5 with ab56238 at 4-8µg/ml. Arrows indicate positively labelled skeletal muscle cells. Magnification: 400X.

References for Anti-TNRC5 antibody (ab56238)

ab56238 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab56238.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up