Overview

  • Product nameAnti-TNRC6B antibody
    See all TNRC6B primary antibodies
  • Description
    Rabbit polyclonal to TNRC6B
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within the N terminal amino acids 180-229 (LQSESGTAPV WSKSTPPAPD NGTSAWGEPN ESSPGWGEMD DTGASTTGWG) of human TNRC6B (NP_001020014).

  • Positive control
    • Human fetal muscle lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified by peptide affinity chromatography method.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 109 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceTNRC6B belongs to the GW182 family. It contains one RRM (RNA recognition motif) domain. TNRC6B plays a role in RNA mediated gene silencing by both micro RNAs (miRNAs) and short interfering RNAs (siRNAs). It is required for miRNA dependent translational repression and siRNA dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. There are three named isoforms.
  • Cellular localizationCytoplasm, P-body. Mammalian P-bodies are also known as GW bodies, GWBs.
  • Database links
  • Alternative names
    • KIAA1093 antibody
    • TNRC 6B antibody
    • Trinucleotide repeat containing 6B antibody
    • Trinucleotide repeat containing gene 6B protein antibody

Anti-TNRC6B antibody images

  • Anti-TNRC6B antibody (ab84308) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 109 kDa
    Observed band size : 109 kDa

References for Anti-TNRC6B antibody (ab84308)

ab84308 has not yet been referenced specifically in any publications.

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