Overview

  • Product nameTobramycin, free base
  • Description
    Ribosomal translation inhibitor
  • Biological descriptionInhibits ribosomal translation. Aminoglycoside antibiotic which binds 30S ribosomal subunit A, preventing functional protein production. Effective against gram-negative bacteria.
  • Purity> 98%

Properties

    References for Tobramycin, free base (ab120659)

    This product has been referenced in:
    • Pignatello R  et al. Amphiphilic ion pairs of tobramycin with lipoamino acids. Eur J Med Chem 46:1665-71 (2011). Read more (PubMed: 21396748) »
    • Hobbie SN  et al. Analysis of the contribution of individual substituents in 4,6-aminoglycoside-ribosome interaction. Antimicrob Agents Chemother 49:5112-8 (2005). Read more (PubMed: 16304180) »
    • Walter F  et al. Binding of tobramycin leads to conformational changes in yeast tRNA(Asp) and inhibition of aminoacylation. EMBO J 21:760-8 (2002). Read more (PubMed: 11847123) »

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