Mouse, Rat, Human Predicted to work with:
Dog, Chimpanzee, Rhesus monkey
Recombinant fragment: GLAGALDARQ QSTGAIPVTQ ACLMEDIEQW LSTDVGNDAE EPKGVTSEEF DKFLEERAKA ADRLPNLSSP SAEGPPGPPS GPAPRKKTQE KDDDMLFA, corresponding to amino acids 394-491 of Human TOM1 (NP_005479) with a proprietory tag.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 54 kDa).
Use at an assay dependent dilution. Detection limit for recombinant tagged TOM1 is approximately 30ng/ml when used as a capture antibody.
RelevanceFunction: May be involved in intracellular trafficking. Probable association with membranes.
Tissue specificity: Widely expressed. Highly expressed in skeletal muscle, heart, placenta and liver.
Similarity: Belongs to the TOM1 family.
Contains 1 GAT domain.
Contains 1 VHS domain.
Cellular localizationCytoplasm. Membrane; Peripheral membrane protein