Overview

  • Product name
  • Description
    Goat polyclonal to TOM1L1
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Cynomolgus monkey
  • Immunogen

    Synthetic peptide:

    C-EQNKNQKEATNTTSE

    , corresponding to internal sequence amino acids 295-309 of Human TOM1L1 (NP_005477.1).

  • Positive control
    • Human Brain (Cerebellum) lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab77601 is purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab77601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: antibody detection limit dilution 1/64000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 53 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.
    • Sequence similarities
      Belongs to the TOM1 family.
      Contains 1 GAT domain.
      Contains 1 VHS domain.
    • Post-translational
      modifications
      Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization
      Golgi apparatus > Golgi stack. Endosome membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2310045L10Rik antibody
      • C80573 antibody
      • OK/KNS CL.3 antibody
      • Src activating and signaling molecule antibody
      • Src activating and signaling molecule protein antibody
      • Src-activating and signaling molecule protein antibody
      • SRCASM antibody
      • Target of Myb like protein 1 antibody
      • Target of Myb-like protein 1 antibody
      • Target of myb1 (chicken) homolog like 1 antibody
      • Target of myb1 (chicken) like 1 antibody
      • Target of myb1 like 1 antibody
      • TM1L1_HUMAN antibody
      • TOM1 L1 antibody
      • TOM1 like protein 1 antibody
      • TOM1-like protein 1 antibody
      • TOM1L1 antibody
      • TOM1L1 protein antibody
      see all

    Images

    References

    ab77601 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab77601.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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