Overview

  • Product name
  • Description
    Rabbit polyclonal to TOP1MT
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 40-143 of Human TOP1MT.

  • Positive control
    • Human colon tissue; RT 4, U 251 MG and Human Plasma lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Relieves DNA strain that arise during duplication of mitochondrial DNA.
  • Tissue specificity
    Ubiquitous; highest in skeletal muscle, heart, brain and fetal liver.
  • Sequence similarities
    Belongs to the eukaryotic type I topoisomerase family.
  • Cellular localization
    Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2900052H09Rik antibody
    • DNA topoisomerase I antibody
    • DNA topoisomerase I, mitochondrial antibody
    • mitochondrial antibody
    • TOP1M_HUMAN antibody
    • TOP1mt antibody
    • Topoisomerase I mitochondrial antibody
    see all

Anti-TOP1MT antibody images

  • ab121681 at 1/175 dilution staining TOP1MT in Paraffin-embedded Human Colon tissue by Immunohistochemistry
  • All lanes : Anti-TOP1MT antibody (ab121681) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique

References for Anti-TOP1MT antibody (ab121681)

ab121681 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121681.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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