Anti-Topoisomerase II alpha antibody [EP1102Y] (ab52934)

Publishing research using ab52934? Please let us know so that we can cite the reference in this datasheet.

ab52934 has been referenced in 15 publications.

  • Connolly NP  et al. Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma. Sci Rep 8:1180 (2018). PubMed: 29352201
  • Zhu QN  et al. LncRNA H19 is a major mediator of doxorubicin chemoresistance in breast cancer cells through a cullin4A-MDR1 pathway. Oncotarget 8:91990-92003 (2017). PubMed: 29190892
  • Shi ZX  et al. Yi-qi-yang-yin-tang increases the sensitivity of KG1a leukemia stem cells to daunorubicin by promoting cell cycle progression and regulating the expression of PTEN, TOPOII and mTOR. Oncol Lett 14:6441-6448 (2017). PubMed: 29163680
  • Kristoffersen EL  et al. Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events. Nucleic Acids Res 45:7855-7869 (2017). PubMed: 28541438
  • Scapulatempo-Neto C  et al. Characterization of topoisomerase II a and minichromosome maintenance protein 2 expression in anal carcinoma. Oncol Lett 13:1891-1898 (2017). IHC-P ; Human . PubMed: 28454340
  • Guturi KK  et al. RNF168 and USP10 regulate topoisomerase IIa function via opposing effects on its ubiquitylation. Nat Commun 7:12638 (2016). PubMed: 27558965
  • Lopez-Mosqueda J  et al. SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks. Elife 5:N/A (2016). WB ; Human . PubMed: 27852435
  • d'Alcontres MS  et al. TopoIIa prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres. Cell Cycle 13:1463-81 (2014). ChIP . PubMed: 24626180
  • Kim MK  et al. Loss of compensatory pro-survival and anti-apoptotic modulator, IKKe, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21. Oncotarget 5:12788-802 (2014). WB . PubMed: 25474241
  • Dykhuizen EC  et al. BAF complexes facilitate decatenation of DNA by topoisomerase IIa. Nature 497:624-7 (2013). IP ; Mouse, Human . PubMed: 23698369
  • Taniai E  et al. Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats. Toxicol Lett 224:64-72 (2013). Rat . PubMed: 24120684
  • Kimura M  et al. Involvement of multiple cell cycle aberrations in early preneoplastic liver cell lesions by tumor promotion with thioacetamide in a two-stage rat hepatocarcinogenesis model. Exp Toxicol Pathol 65:979-88 (2013). Rat . PubMed: 23474136
  • Gardner L  et al. Geminin overexpression prevents the completion of topoisomerase IIa chromosome decatenation, leading to aneuploidy in human mammary epithelial cells. Breast Cancer Res 13:R53 (2011). PubMed: 21595939
  • Park JS  et al. Topoisomerase II alpha as a universal tumor antigen: antitumor immunity in murine tumor models and H-2K(b)-restricted T cell epitope. Cancer Immunol Immunother 59:747-57 (2010). PubMed: 19936747
  • Adler M  et al. Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity. Carcinogenesis 30:711-9 (2009). PubMed: 19237604


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