Total OXPHOS Rodent WB Antibody Cocktail (ab110413)

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ab110413 has been referenced in 153 publications.

  • Lopez-Gomez C  et al. Deoxycytidine and deoxythymidine treatment for thymidine kinase 2 deficiency. Ann Neurol N/A:N/A (2017). Mouse . PubMed: 28318037
  • Dias TR  et al. Implications of epigallocatechin-3-gallate in cultured human Sertoli cells glycolytic and oxidative profile. Toxicol In Vitro N/A:N/A (2017). WB . PubMed: 28323106
  • Kang HT  et al. Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome. Aging Cell N/A:N/A (2017). WB . PubMed: 28317242
  • Timpani CA  et al. Attempting to Compensate for Reduced Neuronal Nitric Oxide Synthase Protein with Nitrate Supplementation Cannot Overcome Metabolic Dysfunction but Rather Has Detrimental Effects in Dystrophin-Deficient mdx Muscle. Neurotherapeutics 14:429-446 (2017). Mouse . PubMed: 27921261
  • Chung E  et al. Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts. Physiol Rep 5:N/A (2017). WB ; Mouse . PubMed: 28292876
  • Gudiksen A & Pilegaard H PGC-1a and fasting-induced PDH regulation in mouse skeletal muscle. Physiol Rep 5:N/A (2017). WB ; Mouse . PubMed: 28400503
  • Monterisi S  et al. PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling. Elife 6:N/A (2017). WB . PubMed: 28463107
  • Ota U  et al. 5-aminolevulinic acid combined with ferrous ion reduces adiposity and improves glucose tolerance in diet-induced obese mice via enhancing mitochondrial function. BMC Pharmacol Toxicol 18:7 (2017). WB ; Mouse . PubMed: 28132645
  • Hogarth MW  et al. Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy. Nat Commun 8:14143 (2017). WB ; Mouse . PubMed: 28139640
  • Cooper HM  et al. ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia. Hum Mol Genet 26:1432-1443 (2017). PubMed: 28158749
  • Chavan H  et al. Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response. Oxid Med Cell Longev 2017:9251303 (2017). WB ; Human . PubMed: 28163822
  • Andres AM  et al. Mitophagy and mitochondrial biogenesis in atrial tissue of patients undergoing heart surgery with cardiopulmonary bypass. JCI Insight 2:e89303 (2017). WB ; Human . PubMed: 28239650
  • Kasch J  et al. Beneficial effects of exercise on offspring obesity and insulin resistance are reduced by maternal high-fat diet. PLoS One 12:e0173076 (2017). PubMed: 28235071
  • Bertolo A  et al. Oxidative status predicts quality in human mesenchymal stem cells. Stem Cell Res Ther 8:3 (2017). WB ; Human . PubMed: 28061861
  • Szibor M  et al. Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology. Dis Model Mech 10:163-171 (2017). Mouse . PubMed: 28067626
  • Fernández-Gil B  et al. Melatonin protects rats from radiotherapy-induced small intestine toxicity. PLoS One 12:e0174474 (2017). WB ; Rat . PubMed: 28403142
  • Hall AR  et al. Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction. Cell Death Dis 7:e2238 (2016). WB ; Mouse . PubMed: 27228353
  • Sverdlov AL  et al. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc 5:N/A (2016). WB ; Mouse . PubMed: 26755553
  • Sabbah HN  et al. Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure. Circ Heart Fail 9:e002206 (2016). WB ; Dog . PubMed: 26839394
  • Vial G  et al. Liver mitochondrial function in ZDF rats during the early stages of diabetes disease. Physiol Rep 4:N/A (2016). WB ; Rat . PubMed: 26847727
  • Kitaoka Y  et al. Nrf2 deficiency does not affect denervation-induced alterations in mitochondrial fission and fusion proteins in skeletal muscle. Physiol Rep 4:N/A (2016). WB ; Mouse . PubMed: 28039408
  • Enos RT  et al. A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. PLoS One 11:e0167979 (2016). WB ; Mouse . PubMed: 27959936
  • Badin PM  et al. Muscle Arnt/Hif1ß Is Dispensable in Myofiber Type Determination, Vascularization and Insulin Sensitivity. PLoS One 11:e0168457 (2016). WB ; Mouse . PubMed: 28005939
  • Li N  et al. Short-term moderate diet restriction in adulthood can reverse oxidative, cardiovascular and metabolic alterations induced by postnatal overfeeding in mice. Sci Rep 6:30817 (2016). PubMed: 27465434
  • Schubert C  et al. Reduction of apoptosis and preservation of mitochondrial integrity under ischemia/reperfusion injury is mediated by estrogen receptor ß. Biol Sex Differ 7:53 (2016). WB ; Mouse . PubMed: 27688871
  • Bowman CE  et al. Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Mol Cell Biol 36:2089-104 (2016). WB ; Mouse . PubMed: 27215380
  • Lühl S  et al. Novel homozygous RARS2 mutation in two siblings without pontocerebellar hypoplasia - further expansion of the phenotypic spectrum. Orphanet J Rare Dis 11:140 (2016). SDS-PAGE ; Human . PubMed: 27769281
  • Albert V  et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med 8:232-46 (2016). WB ; Mouse . PubMed: 26772600
  • Mali VR  et al. Cardiac Mitochondrial Respiratory Dysfunction and Tissue Damage in Chronic Hyperglycemia Correlate with Reduced Aldehyde Dehydrogenase-2 Activity. PLoS One 11:e0163158 (2016). WB . PubMed: 27736868
  • Fiuza-Luces C  et al. Muscle Signaling in Exercise Intolerance: Insights from the McArdle Mouse Model. Med Sci Sports Exerc N/A:N/A (2016). WB . PubMed: 27031745
  • Radde BN  et al. Anacardic Acid, Salicylic Acid, and Oleic Acid Differentially Alter Cellular Bioenergetic Function in Breast Cancer Cells. J Cell Biochem 117:2521-32 (2016). PubMed: 26990649
  • Linden MA  et al. A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95 (2016). PubMed: 27445343
  • Miotto PM & Holloway GP In the absence of phosphate shuttling, exercise reveals the in vivo importance of creatine-independent mitochondrial ADP transport. Biochem J 473:2831-43 (2016). PubMed: 27402793
  • Robinson MM  et al. Release of skeletal muscle peptide fragments identifies individual proteins degraded during insulin deprivation in type 1 diabetic humans and mice. Am J Physiol Endocrinol Metab 311:E628-37 (2016). PubMed: 27436610
  • Delgado-Camprubi M  et al. Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation. Cell Death Differ N/A:N/A (2016). PubMed: 27689878
  • De Rosa V  et al. Early (18)F-FDG uptake as a reliable imaging biomarker of T790M-mediated resistance but not MET amplification in non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors. EJNMMI Res 6:74 (2016). WB . PubMed: 27726115
  • Uddin GM  et al. Head to Head Comparison of Short-Term Treatment with the NAD(+) Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice. Front Pharmacol 7:258 (2016). WB ; Mouse . PubMed: 27594836
  • Svensson K  et al. Loss of Renal Tubular PGC-1a Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice. PLoS One 11:e0158716 (2016). PubMed: 27463191
  • Schultz J  et al. Precise expression of Fis1 is important for glucose responsiveness of beta cells. J Endocrinol 230:81-91 (2016). PubMed: 27179109
  • Mohktar RA  et al. Perilipin 5 is dispensable for normal substrate metabolism and in the adaptation of skeletal muscle to exercise training. Am J Physiol Endocrinol Metab 311:E128-37 (2016). PubMed: 27189934
  • Bal NC  et al. Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function. J Biol Chem 291:17247-57 (2016). PubMed: 27298322
  • Ciapaite J  et al. Fiber-type-specific sensitivities and phenotypic adaptations to dietary fat overload differentially impact fast- versus slow-twitch muscle contractile function in C57BL/6J mice. J Nutr Biochem 26:155-64 (2015). PubMed: 25516489
  • Bruns DR  et al. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am J Physiol Lung Cell Mol Physiol 308:L158-67 (2015). PubMed: 25416385
  • Yuan S  et al. Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism. Stem Cell Res Ther 6:198 (2015). WB . PubMed: 26472041
  • Holloway TM  et al. High-intensity interval and endurance training are associated with divergent skeletal muscle adaptations in a rodent model of hypertension. Am J Physiol Regul Integr Comp Physiol 308:R927-34 (2015). WB ; Rat . PubMed: 25855305
  • Arce-Cerezo A  et al. HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance. Sci Rep 5:14487 (2015). WB ; Mouse . PubMed: 26411793
  • Lee S  et al. Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing. Hum Mol Genet 24:7286-94 (2015). WB ; Mouse . PubMed: 26464487
  • Holloway TM  et al. High intensity interval and endurance training have opposing effects on markers of heart failure and cardiac remodeling in hypertensive rats. PLoS One 10:e0121138 (2015). WB ; Rat . PubMed: 25803693
  • Ishihara T  et al. Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol 35:211-23 (2015). PubMed: 25348719
  • Gospodarska E  et al. Mitochondrial turnover: a phenotype distinguishing brown adipocytes from interscapular brown adipose tissue and white adipose tissue. J Biol Chem 290:8243-55 (2015). WB ; Mouse . PubMed: 25645913
  • Dai W  et al. By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice. Oncotarget 6:13703-17 (2015). WB ; Human . PubMed: 25938543
  • Sheldon RD  et al. Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 308:G540-9 (2015). WB ; Rat . PubMed: 25573175
  • Vial G  et al. Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice model. Diabetes 64:2254-64 (2015). WB ; Mouse . PubMed: 25552598
  • Vieira-Potter VJ  et al. Female rats selectively bred for high intrinsic aerobic fitness are protected from ovariectomy-associated metabolic dysfunction. Am J Physiol Regul Integr Comp Physiol 308:R530-42 (2015). WB ; Rat . PubMed: 25608751
  • Mourier A  et al. Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208:429-42 (2015). WB ; Mouse . PubMed: 25688136
  • Sopariwala DH  et al. Sarcolipin overexpression improves muscle energetics and reduces fatigue. J Appl Physiol (1985) 118:1050-8 (2015). WB ; Mouse . PubMed: 25701006
  • Kleinridders A  et al. Insulin resistance in brain alters dopamine turnover and causes behavioral disorders. Proc Natl Acad Sci U S A 112:3463-8 (2015). WB ; Mouse . PubMed: 25733901
  • Cheung KG  et al. Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes. J Biol Chem 290:10981-93 (2015). WB ; Mouse . PubMed: 25759382
  • Dubé JJ  et al. Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice. Am J Physiol Endocrinol Metab 308:E879-90 (2015). WB ; Mouse . PubMed: 25783895
  • Ludzki A  et al. Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insulin Signaling. Diabetes 64:2769-79 (2015). WB ; Human . PubMed: 25845660
  • Shabalina IG  et al. Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice. FASEB J 29:3274-86 (2015). WB ; Mouse . PubMed: 25900807
  • Svensson K  et al. Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor ? Co-activator 1a (PGC-1a). J Biol Chem 290:16059-76 (2015). WB ; Mouse . PubMed: 25987562
  • Monternier PA  et al. Skeletal muscle phenotype affects fasting-induced mitochondrial oxidative phosphorylation flexibility in cold-acclimated ducklings. J Exp Biol 218:2427-34 (2015). WB . PubMed: 26026038
  • Wall CE  et al. High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice. Proc Natl Acad Sci U S A 112:8714-9 (2015). WB ; Mouse . PubMed: 26124126
  • Ferramosca A  et al. Krill Oil Ameliorates Mitochondrial Dysfunctions in Rats Treated with High-Fat Diet. Biomed Res Int 2015:645984 (2015). WB ; Rat . PubMed: 26301251
  • Viticchiè G  et al. p63 supports aerobic respiration through hexokinase II. Proc Natl Acad Sci U S A 112:11577-82 (2015). WB . PubMed: 26324887
  • Hals IK  et al. Mitochondrial Respiration in Insulin-Producing ß-Cells: General Characteristics and Adaptive Effects of Hypoxia. PLoS One 10:e0138558 (2015). WB ; Rat . PubMed: 26401848
  • Hollis F  et al. Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91 (2015). WB ; Rat . PubMed: 26621716
  • Li M  et al. Role of PKCd in Insulin Sensitivity and Skeletal Muscle Metabolism. Diabetes 64:4023-32 (2015). WB ; Mouse . PubMed: 26307588
  • Sverdlov AL  et al. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol N/A:N/A (2014). WB ; Mouse . PubMed: 25109264
  • Chen M  et al. Impaired glucose metabolism in response to high fat diet in female mice conceived by in vitro fertilization (IVF) or ovarian stimulation alone. PLoS One 9:e113155 (2014). WB ; Mouse . PubMed: 25405530
  • Thomas MM  et al. Early oxidative shifts in mouse skeletal muscle morphology with high-fat diet consumption do not lead to functional improvements. Physiol Rep 2:N/A (2014). PubMed: 25247768
  • Sheedfar F  et al. Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease. Aging (Albany NY) 6:281-95 (2014). WB . PubMed: 24751397
  • Mizumura K  et al. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J Clin Invest 124:3987-4003 (2014). PubMed: 25083992
  • Frederick DW  et al. Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase is not Sufficient to Promote Oxidative Metabolism. J Biol Chem N/A:N/A (2014). PubMed: 25411251
  • Tamura Y  et al. Postexercise whole body heat stress additively enhances endurance training-induced mitochondrial adaptations in mouse skeletal muscle. Am J Physiol Regul Integr Comp Physiol 307:R931-43 (2014). PubMed: 25080501
  • Vernochet C  et al. Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications. FASEB J 28:4408-19 (2014). PubMed: 25005176
  • Tagliaferri C  et al. Increased body fat mass and tissue lipotoxicity associated with ovariectomy or high-fat diet differentially affects bone and skeletal muscle metabolism in rats. Eur J Nutr N/A:N/A (2014). PubMed: 25370302
  • Mulligan CM  et al. Inhibition of Delta-6 Desaturase Reverses Cardiolipin Remodeling and Prevents Contractile Dysfunction in the Aged Mouse Heart Without Altering Mitochondrial Respiratory Function. J Gerontol A Biol Sci Med Sci N/A:N/A (2014). WB ; Mouse . PubMed: 24418793
  • Kanzleiter T  et al. Pknox1/Prep1 regulates mitochondrial oxidative phosphorylation components in skeletal muscle. Mol Cell Biol 34:290-8 (2014). WB . PubMed: 24216763
  • Forterre A  et al. Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? PLoS One 9:e84153 (2014). WB ; Mouse . PubMed: 24392111
  • Latouche C  et al. Maternal overnutrition programs changes in the expression of skeletal muscle genes that are associated with insulin resistance and defects of oxidative phosphorylation in adult male rat offspring. J Nutr 144:237-44 (2014). WB ; Rat . PubMed: 24381224
  • Slot IG  et al. The muscle oxidative regulatory response to acute exercise is not impaired in less advanced COPD despite a decreased oxidative phenotype. PLoS One 9:e90150 (2014). WB ; Human . PubMed: 24587251
  • Burbulla LF  et al. Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1. Cell Death Dis 5:e1180 (2014). WB ; Human . PubMed: 24743735
  • Ost M  et al. Activation of AMPKa2 Is Not Crucial for Mitochondrial Uncoupling-Induced Metabolic Effects but Required to Maintain Skeletal Muscle Integrity. PLoS One 9:e94689 (2014). WB . PubMed: 24732703
  • Wijnen WJ  et al. Cardiomyocyte-specific miRNA-30c over-expression causes dilated cardiomyopathy. PLoS One 9:e96290 (2014). WB . PubMed: 24789369
  • Hall DD  et al. Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival. PLoS One 9:e96866 (2014). WB ; Human . PubMed: 24802861
  • Garcia-Diaz B  et al. Deoxynucleoside stress exacerbates the phenotype of a mouse model of mitochondrial neurogastrointestinal encephalopathy. Brain 137:1337-49 (2014). WB ; Mouse . PubMed: 24727567
  • Sin TK  et al. Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart. J Physiol 592:2535-48 (2014). Mouse . PubMed: 24639483
  • Jain SS  et al. High-fat diet-induced mitochondrial biogenesis is regulated by mitochondrial-derived reactive oxygen species activation of CaMKII. Diabetes 63:1907-13 (2014). WB ; Rat . PubMed: 24520120
  • Garone C  et al. Deoxypyrimidine monophosphate bypass therapy for thymidine kinase 2 deficiency. EMBO Mol Med N/A:N/A (2014). WB ; Mouse . PubMed: 24968719
  • Beaudoin MS  et al. Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats. J Physiol 592:2519-33 (2014). WB ; Rat . PubMed: 24639481
  • Mason RR  et al. Cellular localization and associations of the major lipolytic proteins in human skeletal muscle at rest and during exercise. PLoS One 9:e103062 (2014). IHC-Fr ; Human . PubMed: 25054327
  • Nacarelli T  et al. Inhibition of mTOR Prevents ROS Production Initiated by Ethidium Bromide-Induced Mitochondrial DNA Depletion. Front Endocrinol (Lausanne) 5:122 (2014). WB ; Human . PubMed: 25104948
  • Chow JD  et al. Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation. Mol Metab 3:419-31 (2014). WB ; Mouse . PubMed: 24944901
  • Cao Y  et al. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS One 9:e104104 (2014). WB ; Mouse . PubMed: 25090630
  • Cummins TD  et al. Metabolic remodeling of white adipose tissue in obesity. Am J Physiol Endocrinol Metab 307:E262-77 (2014). PubMed: 24918202
  • Naviaux RK  et al. Antipurinergic therapy corrects the autism-like features in the poly(IC) mouse model. PLoS One 8:e57380 (2013). WB . PubMed: 23516405
  • Ellis JM  et al. Acyl coenzyme A thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity. Mol Cell Biol 33:1869-82 (2013). WB ; Mouse . PubMed: 23459938
  • Galmozzi A  et al. Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue. Diabetes 62:732-42 (2013). WB ; Mouse . PubMed: 23069623
  • Grattagliano I  et al. A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes. World J Gastroenterol 19:3007-17 (2013). PubMed: 23716980
  • Schober G  et al. Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats. J Lipid Res 54:1369-84 (2013). PubMed: 23449193
  • Ma Z  et al. Preconditioning with associated blocking of Ca2+ inflow alleviates hypoxia-induced damage to pancreatic ß-cells. PLoS One 8:e67498 (2013). WB ; Rat . PubMed: 23935835
  • Bär F  et al. Mitochondrial Gene Polymorphisms That Protect Mice From Colitis. Gastroenterology N/A:N/A (2013). WB ; Mouse . PubMed: 23872498
  • Dai Y  et al. Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice. Mitochondrion 13:282-91 (2013). Mouse . PubMed: 23542163
  • Magalhães J  et al. Synergistic impact of endurance training and intermittent hypobaric hypoxia on cardiac function and mitochondrial energetic and signaling. Int J Cardiol 168:5363-71 (2013). WB ; Rat . PubMed: 24012275
  • Bergouignan A  et al. Activity energy expenditure is a major determinant of dietary fat oxidation and trafficking, but the deleterious effect of detraining is more marked than the beneficial effect of training at current recommendations. Am J Clin Nutr 98:648-58 (2013). PubMed: 23902784
  • Trajcevski KE  et al. Enhanced lipid oxidation and maintenance of muscle insulin sensitivity despite glucose intolerance in a diet-induced obesity mouse model. PLoS One 8:e71747 (2013). WB ; Mouse . PubMed: 23951235
  • Sitnick MT  et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes 62:3350-61 (2013). PubMed: 23835334
  • Kleinridders A  et al. Leptin regulation of Hsp60 impacts hypothalamic insulin signaling. J Clin Invest N/A:N/A (2013). WB ; Human coronavirus . PubMed: 24084737
  • Nguyen LM  et al. Effect of near-infrared light exposure on mitochondrial signaling in C2C12 muscle cells. Mitochondrion N/A:N/A (2013). WB ; Mouse . PubMed: 24246911
  • Parl A  et al. The mitochondrial fatty acid synthesis (mtFASII) pathway is capable of mediating nuclear-mitochondrial cross talk through the PPAR system of transcriptional activation. Biochem Biophys Res Commun 441:418-24 (2013). PubMed: 24161390
  • Salabei JK & Hill BG Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation. Redox Biol 1:542-51 (2013). WB . PubMed: 24273737
  • Su YC & Qi X Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation. Hum Mol Genet 22:4545-61 (2013). PubMed: 23813973
  • Kemper MF  et al. Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection. Eur J Pharmacol N/A:N/A (2013). PubMed: 24275351
  • Smith BK  et al. Submaximal ADP-stimulated respiration is impaired in ZDF rats and recovered by resveratrol. J Physiol 591:6089-101 (2013). PubMed: 24081154
  • Gispert S  et al. Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors. Hum Mol Genet N/A:N/A (2013). PubMed: 23851121
  • Caffin F  et al. Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice. J Physiol 591:6017-37 (2013). Mouse . PubMed: 24042504
  • Crane JD  et al. Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle. PLoS One 8:e81879 (2013). WB ; Mouse . PubMed: 24324727
  • Pérez-Schindler J  et al. The transcriptional coactivator PGC-1a is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling. Proc Natl Acad Sci U S A 110:20314-9 (2013). PubMed: 24277823
  • Pearen MA  et al. The nuclear receptor, Nor-1, markedly increases type II oxidative muscle fibers and resistance to fatigue. Mol Endocrinol 26:372-84 (2012). WB ; Mouse . PubMed: 22282471
  • Wang X  et al. Increase in muscle mitochondrial biogenesis does not prevent muscle loss but increased tumor size in a mouse model of acute cancer-induced cachexia. PLoS One 7:e33426 (2012). WB ; Mouse . PubMed: 22428048
  • Finley LW  et al. Skeletal muscle transcriptional coactivator PGC-1a mediates mitochondrial, but not metabolic, changes during calorie restriction. Proc Natl Acad Sci U S A 109:2931-6 (2012). WB . PubMed: 22308395
  • Zheleznova NN  et al. Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb of Henle in the Dahl salt-sensitive rat. Physiol Genomics 44:829-42 (2012). PubMed: 22805345
  • Chao LC  et al. Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. J Lipid Res 53:2610-9 (2012). WB ; Mouse . PubMed: 23028113
  • Hoy AJ  et al. Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation. Endocrinology 152:48-58 (2011). PubMed: 21106876
  • Dorado B  et al. Onset and organ specificity of Tk2 deficiency depends on Tk1 down-regulation and transcriptional compensation. Hum Mol Genet 20:155-64 (2011). PubMed: 20940150
  • Faerber G  et al. Induction of heart failure by minimally invasive aortic constriction in mice: reduced peroxisome proliferator-activated receptor ? coactivator levels and mitochondrial dysfunction. J Thorac Cardiovasc Surg 141:492-500, 500.e1 (2011). PubMed: 20447656
  • Safdar A  et al. Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice. Proc Natl Acad Sci U S A 108:4135-40 (2011). WB ; Mouse . PubMed: 21368114
  • Layne AS  et al. Impaired Muscle AMPK Activation in the Metabolic Syndrome May Attenuate Improved Insulin Action after Exercise Training. J Clin Endocrinol Metab 96:1815-26 (2011). PubMed: 21508135
  • Rector RS  et al. Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model. Am J Physiol Gastrointest Liver Physiol 300:G874-83 (2011). WB ; Rat . PubMed: 21350190
  • Vetterli L  et al. Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism. J Biol Chem 286:6049-60 (2011). WB ; Rat . PubMed: 21163946
  • Wang X & Moraes CT Increases in mitochondrial biogenesis impair carcinogenesis at multiple levels. Mol Oncol : (2011). PubMed: 21855427
  • Usami Y  et al. DJ-1 associates with synaptic membranes. Neurobiol Dis 43:651-62 (2011). WB ; Mouse . PubMed: 21645620
  • Philp A  et al. Sirtuin 1 (SIRT1) Deacetylase Activity Is Not Required for Mitochondrial Biogenesis or Peroxisome Proliferator-activated Receptor-{gamma} Coactivator-1{alpha} (PGC-1{alpha}) Deacetylation following Endurance Exercise. J Biol Chem 286:30561-70 (2011). PubMed: 21757760
  • Yang Y  et al. NAD+-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10. J Biol Chem 285:7417-29 (2010). PubMed: 20042612
  • Rached MT  et al. FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice. J Clin Invest 120:357-68 (2010). PubMed: 20038793
  • Yang H  et al. Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2. Hum Mol Genet 19:170-80 (2010). PubMed: 19837698
  • Hlavácková M  et al. Up-regulation and redistribution of protein kinase C-d in chronically hypoxic heart. Mol Cell Biochem 345:271-82 (2010). PubMed: 20853175
  • Lee-Young RS  et al. Endothelial nitric oxide synthase is central to skeletal muscle metabolic regulation and enzymatic signaling during exercise in vivo. Am J Physiol Regul Integr Comp Physiol 298:R1399-408 (2010). PubMed: 20200137
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