Overview

  • Product nameAnti-TPM4 antibody
    See all TPM4 primary antibodies
  • Description
    Rabbit polyclonal to TPM4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of Human TPM4. NP_003281.1, NP_001138632.1, P67936

  • Positive control
    • U251 Cell Lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThis antibody is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab112567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 29 kDa.

Target

  • FunctionBinds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
  • Tissue specificityDetected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
  • Sequence similaritiesBelongs to the tropomyosin family.
  • DomainThe molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • epididymis secretory protein Li 108 antibody
    • HEL-S-108 antibody
    • TM30p1 antibody
    • TMP 4 antibody
    • TPM4 antibody
    • TPM4_HUMAN antibody
    • Tropomyosin 4 antibody
    • Tropomyosin alpha 4 chain antibody
    • Tropomyosin alpha-4 chain antibody
    • Tropomyosin-4 antibody
    • wu:fb06e07 antibody
    • zgc:103436 antibody
    • zgc:63909 antibody
    see all

Anti-TPM4 antibody images

  • Anti-TPM4 antibody (ab112567) at 1/100 dilution + U251 Cell Lysate at 35 µg

    Predicted band size : 29 kDa

References for Anti-TPM4 antibody (ab112567)

ab112567 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"