Overview

  • Product nameAnti-TPM4 antibody
    See all TPM4 primary antibodies
  • Description
    Mouse monoclonal to TPM4
  • Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-249 of Human TPM4

Properties

Applications

Our Abpromise guarantee covers the use of ab58332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ICC/IF
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IF/ICC: Use at a concentration of 10 µg/ml.
    IHC-P: Use at a concentration of 2 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionBinds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
    • Tissue specificityDetected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
    • Sequence similaritiesBelongs to the tropomyosin family.
    • DomainThe molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
    • Cellular localizationCytoplasm > cytoskeleton.
    • Information by UniProt
    • Database links
    • Alternative names
      • epididymis secretory protein Li 108 antibody
      • HEL-S-108 antibody
      • TM30p1 antibody
      • TMP 4 antibody
      • TPM4 antibody
      • TPM4_HUMAN antibody
      • Tropomyosin 4 antibody
      • Tropomyosin alpha 4 chain antibody
      • Tropomyosin alpha-4 chain antibody
      • Tropomyosin-4 antibody
      • wu:fb06e07 antibody
      • zgc:103436 antibody
      • zgc:63909 antibody
      see all

    Anti-TPM4 antibody images

    • TPM4 antibody (ab58332) used in immunofluorescence at 10ug/ml on HeLa cells.
    • TPM4 antibody (ab58332) used in immunohistochemistry at 2ug/ml on formalin fixed and paraffin embedded human transitional cell carcinoma tissue.


    • Predicted band size : 28 kDa
      TPM4 antibody (ab58332) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-TPM4 antibody (ab58332)

    ab58332 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab58332.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"