Overview

  • Product name
    Anti-TRADD antibody [18A11]
    See all TRADD primary antibodies
  • Description
    Mouse monoclonal [18A11] to TRADD
  • Specificity
    ab49512 recognises human TNFR1-associated death domain protein (TRADD).
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Prokaryotic recombinant fusion protein corresponding to 85 amino acids of exon 2 of the TRADD.

  • Positive control
    • Immunohistochemistry - EBV-positive Hodgkin’s disease.

Properties

Applications

Our Abpromise guarantee covers the use of ab49512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/40 - 1/80.
    High temperature antigen unmasking technique. 60 minutes primary antibody incubation at 25oC.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
    • Tissue specificity
      Found in all examined tissues.
    • Sequence similarities
      Contains 1 death domain.
    • Domain
      Requires the intact DEATH domain to associate with TNFRSF1A/TNFR1.
    • Cellular localization
      Cytoplasm > cytoskeleton.
    • Information by UniProt
    • Database links
    • Alternative names
      • 9130005N23Rik antibody
      • AA930854 antibody
      • TNFR1 associated DEATH domain protein antibody
      • TNFR1-associated DEATH domain protein antibody
      • TNFRSF1A associated via death domain antibody
      • TNFRSF1A-associated via death domain antibody
      • tradd antibody
      • TRADD_HUMAN antibody
      • Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody
      • Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody
      see all

    References

    ab49512 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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