Overview

  • Product nameAnti-TRADD antibody
    See all TRADD primary antibodies
  • Description
    Rabbit polyclonal to TRADD
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 263-312 (EQAFQLLRRF VQAEGRRATL QRLVEALEEN ELTSLAEDLL GLTDPNGGLA) of Human TRADD (NP_003780).

  • Positive control
    • DU145 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab90132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionAdapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
  • Tissue specificityFound in all examined tissues.
  • Sequence similaritiesContains 1 death domain.
  • DomainRequires the intact DEATH domain to associate with TNFRSF1A/TNFR1.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9130005N23Rik antibody
    • AA930854 antibody
    • TNFR1 associated DEATH domain protein antibody
    • TNFR1-associated DEATH domain protein antibody
    • TNFRSF1A associated via death domain antibody
    • TNFRSF1A-associated via death domain antibody
    • tradd antibody
    • TRADD_HUMAN antibody
    • Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody
    • Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody
    see all

Anti-TRADD antibody images

  • Anti-TRADD antibody (ab90132) at 1 µg/ml (in 5% skim milk / PBS buffer) + DU145 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 34 kDa

References for Anti-TRADD antibody (ab90132)

ab90132 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"