Overview

  • Product nameAnti-TRAF4 antibody
    See all TRAF4 primary antibodies
  • Description
    Mouse monoclonal to TRAF4
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: PGAFDNLLEW PFARRVTFSL LDQSDPGLAK PQHVTETFHP DPNWKNFQKP GTWRGSLDES SLGFGYPKFI SHQDIRKRNY VRDDAVFIRA AVELPRKILS , corresponding to amino acids 371-470 of Human TRAF4

Properties

Applications

Our Abpromise guarantee covers the use of ab56613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 1 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAdapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
    • Tissue specificityExpressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus.
    • Sequence similaritiesBelongs to the TNF receptor-associated factor family. B subfamily.
      Contains 1 MATH domain.
      Contains 1 RING-type zinc finger.
      Contains 3 TRAF-type zinc fingers.
    • DomainThe coiled coil domain mediates homo- and hetero-oligomerization.
      The MATH/TRAF domain binds to receptor cytoplasmic domains.
    • Post-translational
      modifications
      Polyubiquitinated, leading to its proteasomal degradation.
    • Cellular localizationCytoplasm. Nucleus. Cytoplasm > perinuclear region. Cell junction > tight junction. Cell membrane. Cytoplasm > cytoskeleton.
    • Information by UniProt
    • Database links
    • Alternative names
      • CART 1 antibody
      • CART1 antibody
      • cysteine rich domain associated with ring and TRAF domain antibody
      • Cysteine rich domain associated with RING and Traf domains protein 1 antibody
      • Cysteine-rich domain associated with RING and Traf domains protein 1 antibody
      • Malignant 62 antibody
      • Metastatic lymph node gene 62 protein antibody
      • MLN 62 antibody
      • MLN62 antibody
      • RING finger protein 83 antibody
      • RNF 83 antibody
      • RNF83 antibody
      • TNF receptor associated factor 4 antibody
      • TNF receptor-associated factor 4 antibody
      • TRAF 4 antibody
      • Traf4 antibody
      • TRAF4_HUMAN antibody
      • tumor necrosis receptor-associated factor 4A antibody
      see all

    Anti-TRAF4 antibody images

    • TRAF4 antibody (ab56613) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human salivary gland.
    • Western blot against tagged recombinant protein immunogen using ab56613 TRAF4 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-TRAF4 antibody (ab56613)

    ab56613 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56613.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"