Overview

  • Product nameAnti-TRAF5 antibody
    See all TRAF5 primary antibodies
  • Description
    Rabbit polyclonal to TRAF5
  • Tested applicationsSuitable for: WB, IHC-P, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human, Gerbil
  • Immunogen

    Synthetic peptide:

    MAHSEEQAAVPCAFIRQNSG

    , corresponding to N terminal amino acids 1-20 of Mouse TRAF5

  • Positive control
    • Spleen, lymphoid, many cancer cell lines.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: Whole serum
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab47539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 65 kDa (predicted molecular weight: 64 kDa).
IHC-P Use at an assay dependent concentration.
IP 1/50 - 1/200.

Target

  • FunctionAdapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis.
  • Tissue specificityExpressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
  • Sequence similaritiesBelongs to the TNF receptor-associated factor family. A subfamily.
    Contains 1 MATH domain.
    Contains 1 RING-type zinc finger.
    Contains 2 TRAF-type zinc fingers.
  • DomainThe MATH/TRAF domain binds to receptor cytoplasmic domains.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC:39780 antibody
    • RING finger protein 84 antibody
    • RNF 84 antibody
    • RNF84 antibody
    • TNF receptor associated factor 5 antibody
    • TNF receptor-associated factor 5 antibody
    • TRAF 5 antibody
    • Traf5 antibody
    • TRAF5_HUMAN antibody
    see all

Anti-TRAF5 antibody images

  • All lanes : Anti-TRAF5 antibody (ab47539) at 1/2000 dilution

    Lane 1 : Normal human testis tissue
    Lane 2 : Normal human kidney tissue
    Lane 3 : Normal human pancreas tissue
    Lane 4 : Normal human liver tissue
    Lane 5 : Normal human prostate tissue
    Lane 6 : Normal human breast tissue
    Lane 7 : Normal human colon tissue
    Lane 8 : Normal human thymus tissue
    Lane 9 : Normal human lymph node tissue
    Lane 10 : Normal human spleen tissue
    Lane 11 : Normal human lung tissue
    Lane 12 : Normal human aorta tissue
    Lane 13 : Normal human epidermis tissue


    Predicted band size : 64 kDa
    Observed band size : 64 kDa
  • Formalin-fixed, paraffin-embedded mouse spleen stained for TRAF5 expression using ab47539 at 1:2000. Hematoxylin-eosin counterstain. A1 is a higher magnification of A.
  • Formalin-fixed, paraffin-embedded mouse tissue stained for TRAF5 expression using ab47539 at 1:2000. Hematoxylin-eosin counterstain.

    A, thymus.

    B, bone marrow.

References for Anti-TRAF5 antibody (ab47539)

ab47539 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"