Validated using a knockout cell line

Anti-TRAF6 antibody [EP591Y] (ab33915)

Publishing research using ab33915? Please let us know so that we can cite the reference in this datasheet.

ab33915 has been referenced in 24 publications.

  • Chen Y  et al. MicroRNA-146a-5p attenuates irradiation-induced and LPS-induced hepatic stellate cell activation and hepatocyte apoptosis through inhibition of TLR4 pathway. Cell Death Dis 9:22 (2018). WB ; Mouse . PubMed: 29348414
  • Morale MG  et al. HPV-transformed cells exhibit altered HMGB1-TLR4/MyD88-SARM1 signaling axis. Sci Rep 8:3476 (2018). WB . PubMed: 29472602
  • Kitamura H  et al. Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells. Mediators Inflamm 2017:6909415 (2017). PubMed: 29138532
  • Wu C  et al. Inhibition of intimal hyperplasia in murine aortic allografts by administration of a small-molecule TLR4 inhibitor TAK-242. Sci Rep 7:15799 (2017). PubMed: 29150694
  • Liu X  et al. Improvement in cerebral ischemia-reperfusion injury through the TLR4/NF-?B pathway after Kudiezi injection in rats. Life Sci 191:132-140 (2017). PubMed: 29080695
  • Kim E  et al. Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6. Sci Adv 3:e1602296 (2017). WB ; Mouse . PubMed: 28439546
  • Zhuang C  et al. TRAF6 regulates the effects of polarized maturation of tolerability: Marrow-derived dendritic cells on collagen-induced arthritis in mice. Biomed Rep 6:206-210 (2017). PubMed: 28357074
  • Li M  et al. microRNA-146a promotes mycobacterial survival in macrophages through suppressing nitric oxide production. Sci Rep 6:23351 (2016). PubMed: 27025258
  • Meininger I  et al. Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells. Nat Commun 7:11292 (2016). Mouse . PubMed: 27068814
  • Li XJ  et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-?B signaling pathways in osteoprotegerin knockout mice. Int J Mol Med N/A:N/A (2016). WB ; Mouse . PubMed: 27840967
  • Padrão AI  et al. Endurance training prevents TWEAK but not myostatin-mediated cardiac remodelling in cancer cachexia. Arch Biochem Biophys 567:13-21 (2015). PubMed: 25575785
  • Alexander M  et al. Exosome-delivered microRNAs modulate the inflammatory response to endotoxin. Nat Commun 6:7321 (2015). PubMed: 26084661
  • Qi Y  et al. Retinal ischemia/reperfusion injury is mediated by Toll-like receptor 4 activation of NLRP3 inflammasomes. Invest Ophthalmol Vis Sci 55:5466-75 (2014). PubMed: 25097240
  • Zhang Y  et al. Ablation of Akt2 protects against lipopolysaccharide-induced cardiac dysfunction: role of Akt ubiquitination E3 ligase TRAF6. J Mol Cell Cardiol 74:76-87 (2014). WB ; Mouse . PubMed: 24805195
  • Ansell SM  et al. Activation of TAK1 by MYD88 L265P drives malignant B-cell Growth in non-Hodgkin lymphoma. Blood Cancer J 4:e183 (2014). WB ; Human . PubMed: 24531446
  • He X  et al. Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica. PLoS One 9:e104323 (2014). WB ; Mouse . PubMed: 25116007
  • Padrão AI  et al. Bladder cancer-induced skeletal muscle wasting: disclosing the role of mitochondria plasticity. Int J Biochem Cell Biol 45:1399-409 (2013). PubMed: 23608519
  • Casella CR & Mitchell TC Inefficient TLR4/MD-2 heterotetramerization by monophosphoryl lipid A. PLoS One 8:e62622 (2013). WB ; Mouse . PubMed: 23638128
  • Iwata J  et al. Modulation of noncanonical TGF-ß signaling prevents cleft palate in Tgfbr2 mutant mice. J Clin Invest 122:873-85 (2012). WB ; Mouse . PubMed: 22326956
  • Chaudhry SI  et al. Autocrine IL-1ß-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFa signalling to carcinoma-associated fibroblasts. Oncogene : (2012). ICC/IF . PubMed: 22450746
  • Chen GY  et al. Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide. Biomaterials 33:6559-69 (2012). ICC/IF, Flow Cyt ; Mouse . PubMed: 22704844
  • Xiao X  et al. OX40 signaling favors the induction of T(H)9 cells and airway inflammation. Nat Immunol 13:981-90 (2012). PubMed: 22842344
  • West AP  et al. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature 472:476-80 (2011). WB ; Mouse . PubMed: 21525932
  • Gribar SC  et al. Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis. J Immunol 182:636-46 (2009). WB ; Human . PubMed: 19109197


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