Overview

  • Product nameAnti-TRAFD1 antibody [2368C3a]
    See all TRAFD1 primary antibodies
  • Description
    Mouse monoclonal [2368C3a] to TRAFD1
  • Tested applicationsSuitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment from internal sequence of Human TRAFD1 (NM_006700).

  • Positive control
    • Recombinant Human TRAFD1 protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab84878 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Filtered through a 0.22 µm membrane.
  • ClonalityMonoclonal
  • Clone number2368C3a
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 65 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • FunctionNegative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
  • Sequence similaritiesContains 1 TRAF-type zinc finger.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLN29 antibody
    • FLN29 gene product antibody
    • Protein FLN29 antibody
    • TRAD1_HUMAN antibody
    • TRAF type zinc finger domain containing 1 antibody
    • TRAF type zinc finger domain containing protein 1 antibody
    • TRAF-type zinc finger domain-containing protein 1 antibody
    • TRAFD 1 antibody
    • TRAFD1 antibody
    see all

Anti-TRAFD1 antibody [2368C3a] images

References for Anti-TRAFD1 antibody [2368C3a] (ab84878)

ab84878 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"