Overview

  • Product nameAnti-TRAFD1 antibody
    See all TRAFD1 primary antibodies
  • Description
    Rabbit polyclonal to TRAFD1
  • Tested applicationsSuitable for: IHC-P, ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Dog
  • Immunogen

    Synthetic peptide derived from a region between residues 395 - 444 of human TRAFD1.

    .

  • Positive control
    • Raji cell lysate for Western blot, and Epithelial cells of human renal tubule for Immunohistochemisty.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None.
    Constituents: 2% Sucrose, PBS.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab25942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA 1/62500.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 63 kDa (predicted molecular weight: 65 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionNegative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
  • Sequence similaritiesContains 1 TRAF-type zinc finger.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLN29 antibody
    • FLN29 gene product antibody
    • Protein FLN29 antibody
    • TRAD1_HUMAN antibody
    • TRAF type zinc finger domain containing 1 antibody
    • TRAF type zinc finger domain containing protein 1 antibody
    • TRAF-type zinc finger domain-containing protein 1 antibody
    • TRAFD 1 antibody
    • TRAFD1 antibody
    see all

Anti-TRAFD1 antibody images

  • Anti-TRAFD1 antibody (ab25942) at 1 µg/ml + Raji cell lysate.

    Predicted band size : 65 kDa
    Observed band size : 63 kDa (why is the actual band size different from the predicted?)
  • Ab25942 at a 4-8µg/ml dilution, staining epithelial cells of human kidney renal tubules by IHC-P. Magnification: X400.

References for Anti-TRAFD1 antibody (ab25942)

ab25942 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"