Overview

  • Product nameAnti-TRAIL antibody
    See all TRAIL primary antibodies
  • Description
    Rabbit polyclonal to TRAIL
  • SpecificityHuman.
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human TRAIL aa 261-277 (C terminal).
    Sequence:

    CTNEHLIDMDHEASFFGA


    (Peptide available as ab7867)

  • Positive control
    • HeLa whole cell lysate.
  • General notesLigand for DR4 and DR5.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab2056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notesIHC-P: Use at a concentration of 20 µg/ml.
    WB: (1:500) gives a 32 kD band. This represents the membrane-bound form of TRAIL.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
    • Tissue specificityWidespread; most predominant in spleen, lung and prostate.
    • Sequence similaritiesBelongs to the tumor necrosis factor family.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Apo 2 ligand antibody
      • APO 2L antibody
      • Apo-2 ligand antibody
      • Apo-2L antibody
      • APO2L antibody
      • CD253 antibody
      • CD253 antigen antibody
      • Chemokine tumor necrosis factor ligand superfamily member 10 antibody
      • Protein TRAIL antibody
      • TL2 antibody
      • TNF Related Apoptosis Inducing Ligand antibody
      • TNF related apoptosis inducing ligand TRAIL antibody
      • TNF-related apoptosis-inducing ligand antibody
      • TNF10_HUMAN antibody
      • TNFSF10 antibody
      • TRAIL antibody
      • Tumor necrosis factor (ligand) family member 10 antibody
      • Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody
      • Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody
      • Tumor necrosis factor ligand superfamily member 10 antibody
      see all

    Anti-TRAIL antibody images

    • Western blot analysis of HeLa cell lysate containing 10, 2.5, or 1 ng of recombinant protein containing extracellular domain of TRAIL with anti-TRAIL at 1 µg/ml.
    • Immunohistochemistry of TRAIL in human brain tissue with TRAIL antibody at 20 µg/ml.

    References for Anti-TRAIL antibody (ab2056)

    ab2056 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. We currently sell the following antibodies that meet your description:

    ab2435 - immunogen: C-terminal; tested species: mouse, human; tested applications: IHC-P, IHC-Fr, IP, WB, ICC/IF

    ab42121 - immunogen...

    Read More

    Thank you for your enquiry. Ab2056 recognizes both the whole TRAIL protein (32 kDa) as well as its extracellular domain (19 kDa). If you are running a Western with HeLa whole cell lysate (which is recommended for a positive control) you would expec...

    Read More

    Yes, the antibody does recognise native human TRAIL in reducing and non-reducing gels.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"