Overview

  • Product nameAnti-TRAIL antibody
    See all TRAIL primary antibodies
  • Description
    Rabbit polyclonal to TRAIL
  • Tested applicationsSuitable for: ELISA, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from internal of human CD253.

  • Positive control
    • Extracts from 293 cells and HUVEC cells, and A549 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab65121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.
WB 1/500 - 1/1000. Detects a band of approximately 32 kDa (predicted molecular weight: 32 kDa).

Target

  • FunctionCytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
  • Tissue specificityWidespread; most predominant in spleen, lung and prostate.
  • Sequence similaritiesBelongs to the tumor necrosis factor family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apo 2 ligand antibody
    • APO 2L antibody
    • Apo-2 ligand antibody
    • Apo-2L antibody
    • APO2L antibody
    • CD253 antibody
    • CD253 antigen antibody
    • Chemokine tumor necrosis factor ligand superfamily member 10 antibody
    • Protein TRAIL antibody
    • TL2 antibody
    • TNF Related Apoptosis Inducing Ligand antibody
    • TNF related apoptosis inducing ligand TRAIL antibody
    • TNF-related apoptosis-inducing ligand antibody
    • TNF10_HUMAN antibody
    • TNFSF10 antibody
    • TRAIL antibody
    • Tumor necrosis factor (ligand) family member 10 antibody
    • Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody
    • Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody
    • Tumor necrosis factor ligand superfamily member 10 antibody
    see all

Anti-TRAIL antibody images

  • These images show A549 cells, stained with ab65121 at 1/500 - 1/1000 dilution; with and without the immunising peptide.
  • All lanes : Anti-TRAIL antibody (ab65121) at 1/500 dilution

    Lane 1 : extracts from 293 cells
    Lane 2 : extracts from Huvec cells
    Lane 3 : extracts from Huvec cells with immunising peptide


    Predicted band size : 32 kDa
    Observed band size : 32 kDa
    Additional bands at : ~48 kDa,~60 kDa. We are unsure as to the identity of these extra bands.

References for Anti-TRAIL antibody (ab65121)

ab65121 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab65121.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"