Overview

  • Product name
    Anti-Transaldolase 1 antibody
    See all Transaldolase 1 primary antibodies
  • Description
    Rabbit polyclonal to Transaldolase 1
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Horse, Guinea pig, Dog, Pig, Chimpanzee, Cynomolgus monkey, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide within Human Transaldolase 1 aa 200-250. The exact sequence is proprietary. NP_006746.1.
    Sequence:

    NTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAG C


    Database link: P37837

  • Positive control
    • HeLa, 293T, Jurkat, TCMK1 and NIH 3T3 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab187689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 38 kDa.
IP Use at 2-10 µg/mg of lysate.

Target

  • Function
    Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  • Pathway
    Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
  • Involvement in disease
    Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris.
  • Sequence similarities
    Belongs to the transaldolase family. Type 1 subfamily.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dihydroxyacetone transferase antibody
    • EC 2.2.1.2 antibody
    • EPS8L2 antibody
    • Glycerone transferase antibody
    • TAL antibody
    • TAL H antibody
    • TALDO antibody
    • TALDO_HUMAN antibody
    • TALDO1 antibody
    • TALDOR antibody
    • TALH antibody
    • Transaldolase 1 antibody
    • Transaldolase antibody
    see all

Images

  • All lanes : Anti-Transaldolase 1 antibody (ab187689) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate
    Lane 2 : 293T whole cell lysate
    Lane 3 : Jurkat whole cell lysate
    Lane 4 : TCMK1 whole cell lysate
    Lane 5 : NIH 3T3 whole cell lysate

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique

    Predicted band size : 38 kDa


    Exposure time : 3 minutes
  • Detection of Transaldolase 1 by Western Blot of Immunoprecipitate.
    ab187689 at 0.4µg/ml labeling Transaldolase 1 in HeLa whole cell lysate immunoprecipitated using ab187689 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.

References

ab187689 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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