The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: 1/500 - 1/1000. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).
Detection Antibody Pair
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionTransaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
PathwayCarbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
Involvement in diseaseDefects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris.
Sequence similaritiesBelongs to the transaldolase family. Type 1 subfamily.