Anti-Transcription termination factor 1 antibody (ab104418)

Overview

  • Product nameAnti-Transcription termination factor 1 antibody
    See all Transcription termination factor 1 primary antibodies
  • Description
    Rabbit polyclonal to Transcription termination factor 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide: RRASQTPAQE TLESEWPQKA KRKKRRREPQ TPAQETLESE WPQKAKKKKR, corresponding to N terminal amino acids 51 - 100 of Mouse Transcription termination factor 1.

  • Positive control
    • Mouse heart lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab104418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 98 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMultifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
  • Sequence similaritiesContains 2 Myb-like domains.
  • DomainThe N-terminal region (NRD) inhibits DNA-binding via its interaction with the C-terminal region.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus. Nucleus > nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • RNA polymerase I termination factor antibody
    • Transcription termination factor 1 antibody
    • Transcription termination factor I antibody
    • Transcription termination factor RNA polymerase I antibody
    • TTF 1 antibody
    • TTF-1 antibody
    • TTF-I antibody
    • Ttf1 antibody
    • TTF1_HUMAN antibody
    see all

Anti-Transcription termination factor 1 antibody images

  • Anti-Transcription termination factor 1 antibody (ab104418) at 1 µg/ml + Mouse heart lysate at 10 µg

    Predicted band size : 98 kDa

References for Anti-Transcription termination factor 1 antibody (ab104418)

ab104418 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"