Overview

  • Product nameAnti-Transferrin antibody [2A2]
    See all Transferrin primary antibodies
  • Description
    Mouse monoclonal [2A2] to Transferrin
  • SpecificityReacts with the N-terminal domain of human transferrin (Kd 2.85 X 10-11). Does not cross react with mouse rabbit or bovine transferrin or with human lactoferrin.
  • Tested applicationsSuitable for: ELISA, Functional Studies, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified transferrin from pooled human plasma.

  • General notesConcentration varies from lot to lot and can be provided on request.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab10211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
Functional Studies Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

Target

  • FunctionTransferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
  • Tissue specificityExpressed by the liver and secreted in plasma.
  • Involvement in diseaseDefects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
  • Sequence similaritiesBelongs to the transferrin family.
    Contains 2 transferrin-like domains.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apotransferrin antibody
    • Beta 1 metal binding globulin antibody
    • Beta-1 metal-binding globulin antibody
    • DKFZp781D0156 antibody
    • PRO1400 antibody
    • PRO1557 antibody
    • PRO2086 antibody
    • Serotransferrin antibody
    • Serotransferrin precursor antibody
    • Siderophilin antibody
    • TF antibody
    • TFQTL1 antibody
    • Transferin antibody
    • Transferrin antibody
    • TRFE_HUMAN antibody
    see all

References for Anti-Transferrin antibody [2A2] (ab10211)

ab10211 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"