Anti-Transglutaminase 6 antibody (ab105725)

Overview

  • Product nameAnti-Transglutaminase 6 antibody
    See all Transglutaminase 6 primary antibodies
  • Description
    Rabbit polyclonal to Transglutaminase 6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 418-467 (KKIGRCISTK AVGSDSRVDI TDLYKYPEGS RKERQVYSKA VNRLFGVEAS) of Human Transglutaminase 6 (CAI22900; UniProt ID O95932 isoform 2).

  • Positive control
    • NTERA2 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. TGM6 has two isoforms- 71 and 79kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCatalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
  • Involvement in diseaseDefects in TGM6 are the cause of spinocerebellar ataxia type 35 (SCA35) [MIM:613908]. A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA35 patients commonly show upper limb involvement and torticollis. There is no cognitive impairment.
  • Sequence similaritiesBelongs to the transglutaminase superfamily. Transglutaminase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Protein-glutamine gamma-glutamyltransferase 6 antibody
    • TG6 antibody
    • TGase Y antibody
    • TGase-3-like antibody
    • TGase-6 antibody
    • TGM3L_HUMAN antibody
    • TGM6 antibody
    • TGY antibody
    • Transglutaminase Y antibody
    • Transglutaminase-3-like antibody
    • Transglutaminase-6 antibody
    see all

Anti-Transglutaminase 6 antibody images

  • Anti-Transglutaminase 6 antibody (ab105725) at 0.5 µg/ml + NTERA2 cell lysate at 10 µg

References for Anti-Transglutaminase 6 antibody (ab105725)

ab105725 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105725.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"