Anti-Transglutaminase 6 antibody (ab126858)

Overview

  • Product name
    Anti-Transglutaminase 6 antibody
    See all Transglutaminase 6 primary antibodies
  • Description
    Goat polyclonal to Transglutaminase 6
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Cow, Dog, Human
  • Immunogen

    Synthetic peptide:

    DKYVDSYGRTLED

    with a Cysteine residue linker, corresponding to internal sequence amino acids 311-323 of Mouse Transglutaminase 6 (NP_808394.1).

  • Positive control
    • Rat lung tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab126858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 79 kDa).

Target

  • Function
    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
  • Involvement in disease
    Defects in TGM6 are the cause of spinocerebellar ataxia type 35 (SCA35) [MIM:613908]. A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA35 patients commonly show upper limb involvement and torticollis. There is no cognitive impairment.
  • Sequence similarities
    Belongs to the transglutaminase superfamily. Transglutaminase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Protein-glutamine gamma-glutamyltransferase 6 antibody
    • TG6 antibody
    • TGase Y antibody
    • TGase-3-like antibody
    • TGase-6 antibody
    • TGM3L_HUMAN antibody
    • TGM6 antibody
    • TGY antibody
    • Transglutaminase Y antibody
    • Transglutaminase-3-like antibody
    • Transglutaminase-6 antibody
    see all

Images

  • Anti-Transglutaminase 6 antibody (ab126858) at 2 µg/ml (for one hour) + Rat lung tissue lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 79 kDa

References

ab126858 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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