Anti-Translation factor GUF1, mitochondrial antibody (ab110951)

Overview

  • Product name
    Anti-Translation factor GUF1, mitochondrial antibody
    See all Translation factor GUF1, mitochondrial primary antibodies
  • Description
    Rabbit polyclonal to Translation factor GUF1, mitochondrial
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthesized peptide derived from an internal region of Human Translation factor GUF1, mitochondrial.

  • Positive control
    • Human colon carcinoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, PBS, 0.88% Sodium chloride
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab110951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
  • Sequence similarities
    Belongs to the GTP-binding elongation factor family. LepA subfamily.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EF-4 antibody
    • Elongation factor 4 homolog antibody
    • GTPase GUF1 antibody
    • GUF1 antibody
    • GUF1_HUMAN antibody
    • mitochondrial antibody
    • Ribosomal back-translocase antibody
    • Translation factor guf1 antibody
    see all

Anti-Translation factor GUF1, mitochondrial antibody images

  • Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue, using 1/50 ab111951. The picture on the right is treated with the synthesized peptide.

References for Anti-Translation factor GUF1, mitochondrial antibody (ab110951)

ab110951 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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