Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Belongs to the GTP-binding elongation factor family. LepA subfamily.
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human prostate carcinoma tissue labeling Translation factor GUF1, mitochondrial with ab171161 at 1/10 dilution followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot - Anti-Translation factor GUF1, mitochondrial antibody - N-terminal (ab171161)
Anti-Translation factor GUF1, mitochondrial antibody - N-terminal (ab171161) at 1/100 dilution + HepG2 cell line lysate at 35 µg Developed using the ECL technique