The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at a concentration of 1-5 µg/ml. IHC-P: Use at a concentration of 1 µg/ml.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
FunctionTRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Sequence similaritiesBelongs to the TRAP-alpha family.
DomainShows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
Translocon associated protein alpha subunit antibody
Translocon associated protein subunit alpha antibody
Translocon-associated protein subunit alpha antibody
TRAP a antibody
Anti-TRAP alpha antibody images
IHC-P - TRAP alpha antibody (ab58008)
TRAP alpha antibody (ab58008) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human tonsil.
Western blot - TRAP alpha antibody (ab58008)
Predicted band size : 32 kDa TRAP alpha antibody (ab58008) at 1ug/lane + A-431 cell lysate at 25ug/lane.
References for Anti-TRAP alpha antibody (ab58008)
This product has been referenced in:
Park SH et al. Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER network. J Clin Invest120:1097-110 (2010).
Read more (PubMed: 20200447) »