Overview

  • Product name
  • Description
    Rabbit polyclonal to TRAPPC2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 10-39 of Human TRAPPC2 (NP_055378.1, NP_001011658.1)

  • Positive control
    • NCI-H292 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab123959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 16 kDa.

Target

  • Function
    Prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. May play a role in vesicular transport from endoplasmic reticulum to Golgi.
  • Tissue specificity
    Widely expressed.
  • Involvement in disease
    Defects in TRAPPC2 are the cause of spondyloepiphyseal dysplasia tarda (SEDT) [MIM:313400]. SEDT is an X-linked recessive disorder of endochondral bone formation.
  • Sequence similarities
    Belongs to the TRAPP small subunits family. Sedlin subfamily.
  • Cellular localization
    Cytoplasm > perinuclear region. Endoplasmic reticulum. Golgi apparatus. Localized in perinuclear granular structures.
  • Information by UniProt
  • Database links
  • Alternative names
    • hYP38334 antibody
    • MBP 1 interacting protein 2A antibody
    • MBP-1-interacting protein 2A antibody
    • MIP 2A antibody
    • MIP-2A antibody
    • MIP2A antibody
    • SEDL antibody
    • Sedlin antibody
    • SEDLP antibody
    • SEDT antibody
    • Spondyloepiphyseal dysplasia tarda protein antibody
    • Spondyloepiphyseal dysplasia, late antibody
    • TPPC2_HUMAN antibody
    • Trafficking protein particle complex 2 antibody
    • Trafficking protein particle complex subunit 2 antibody
    • TRAPPC2P1 antibody
    • TRS20 antibody
    • ZNF547L antibody
    see all

Images

  • Anti-TRAPPC2 antibody (ab123959) at 1/100 dilution + Human cell line NCI-H292 lysate at 35 µg

    Predicted band size : 16 kDa

References

ab123959 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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